Chlorella

Nutrient-dense freshwater algae that supports detoxification, immune function, and provides complete nutrition

Scientific nameChlorella vulgaris/pyrenoidosa FormulaComplex nutrients and chlorophyll Molecular weightVariable biological compounds g/mol CASVarious natural compounds

85 absorption score

8 safety / 10

35 USD per month

5 documented interactions

Check it against something

Evidence level B

Chlorella with:

78 out of 100

Works better together Take together — same timing window amplifies the synergy.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Heavy metal detoxification

Binds and removes heavy metals and toxins from the body

Cell wall components chelate heavy metals facilitating elimination Evidence B-grade 4-12 weeks

Enhanced immune system function

Supports immune response and may reduce infection risk

Rich in nutrients and compounds that modulate immune function Evidence B-grade 2-8 weeks

Complete nutritional support

Provides comprehensive nutrition including protein and vitamins

Nutrient-dense superfood with complete amino acid profile Evidence A-grade Immediate nutritional benefits

Improved energy and vitality

Enhances energy levels and overall vitality

Rich in B vitamins, iron, and chlorophyll supporting energy production Evidence C-grade 2-6 weeks

Digestive and gut health support

Supports healthy gut bacteria and digestive function

Prebiotic effects and digestive enzyme support Evidence C-grade 2-8 weeks

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Turmeric Anti-inflammatory & antioxidant 300-1000mg A 3% Glutathione Master antioxidant & detox support 250-750mg B 20% Astaxanthin Superior antioxidant & skin protection 4-12mg B 20% SAM-e Mood support & liver health 400-800mg A 70% Plant Collagen Vegan collagen support & antioxidants 2-5g C 70% Quercetin Immune support & allergy relief 500-1000mg B 5%

Every pair we checked

12 combinations scored by the engine

Chlorella + Caffeine No documented interaction either way No known interaction 70

Chlorella + Creatine Monohydrate No documented interaction either way No known interaction 70

Chlorella + Calcium Carbonate No documented interaction either way No known interaction 70

Chlorella + Whey Protein No documented interaction either way No known interaction 70

Chlorella + Lactase No documented interaction either way No known interaction 70

Chlorella + Bovine Collagen No documented interaction either way No known interaction 70

Chlorella + DHA No documented interaction either way No known interaction 70

Chlorella + Turmeric No documented interaction either way No known interaction 70

Chlorella + Fish Oil (EPA/DHA) No documented interaction either way No known interaction 70

Chlorella + Magnesium Oxide No documented interaction either way No known interaction 70

Chlorella + Spirulina Enhanced nutritional and detox benefits Works better together 78

Chlorella + Vitamin D3 Enhanced heavy metal chelation and detox Works better together 78

Dosage

With meals

Daily3-10g

Nutritional support3-6g daily

Detoxification5-10g daily

Heavy metal chelation10-20g daily

Immune support3-6g daily

When to expect it

First Effects1-2 weeks for energy and nutritional benefits

Peak Benefits8-16 weeks for sustained detox and immune benefits

Deficiency DevelopmentReturn to baseline nutrition and toxin levels

Toxicity OnsetVery rare, mainly initial detox symptoms

How to measure it

$200-400

MarkerHeavy metal levels or nutritional status markers

OptimalReduced heavy metal levels and improved nutritional markers

Deficient belowNot applicable for supplement

FrequencyEvery 6-12 months for heavy metal monitoring if detoxing

What people actually reported to the FDA

CAERS, 33 reports naming it as the suspect

Most reported effects

Vomiting 17

Diarrhoea 9

Nausea 6

Malaise 5

Loss of consciousness 3

Named as the suspect 33 reports of 46 that mention it at all

Serious outcome 88% hospitalisation, emergency room or worse

Other Serious or Important Medical Event15

Hospitalization12

Life Threatening6

Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →

What actually reaches you

The label counts the carrier, your body does not

Absorption Very high 85 of 100 · best absorbed form of this compound

Delivered daily 5525 mg

Cost per 100 mg delivered $0.02 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented

Spirulina

Enhanced nutritional and detox benefits

Complementary algae with overlapping but distinct nutrient profiles · level B

Vitamin C

Enhanced heavy metal chelation and detox

Vitamin C supports heavy metal elimination and immune function · level B

Cilantro

Enhanced heavy metal detoxification

Cilantro mobilizes metals while chlorella binds and removes them · level C

What not to take with Chlorella

2 documented

Medications Taken Together

May bind some medications reducing absorption

Fiber and chelating properties may bind drugs · moderate significance

Coffee Tea Tannins

Tannins may reduce mineral absorption

Tannins bind minerals reducing bioavailability · minor significance

Medication interactions

Discuss these with a pharmacist before combining

blood-thinners Moderate

High vitamin K content may affect blood clotting

What to do: Monitor INR if using large amounts

immunosuppressants Minor

May stimulate immune function

What to do: Monitor immune status

thyroid-medications Minor

Iodine content may affect thyroid function

What to do: Monitor thyroid function

Available forms

bioavailability compared

Cracked Cell Wall Chlorella 85

Chlorella Extract/Concentrate 90

Cracked Cell Wall Chlorella: Better absorption, Complete nutrition, Detox support, Cracked cell wall

Chlorella Extract/Concentrate: Higher potency, Smaller doses, Concentrated benefits, Better tolerance

Food sources

before you supplement

Chlorella tablets/powder Pure concentrated form · 85

Green superfood blends Variable chlorella content · 75

Not found in common foods Supplementation required · N/A

Fresh chlorella (rare) Highest nutrient density · 90

Too little

deficiency signs

Poor detoxification capacity and toxin accumulation
Nutritional deficiencies especially B vitamins and protein
Compromised immune function and frequent infections
Low energy and chronic fatigue
Poor gut health and digestive issues
Increased susceptibility to environmental toxins
Slow healing and recovery

Too much

toxicity signs

Generally safe but potential reactions:
Initial digestive upset and nausea
Temporary detox symptoms (headaches, fatigue)
Possible iodine sensitivity in thyroid disorders
Rare allergic reactions

Who benefits most

heavy-metal-detox

Excellent for binding and removing heavy metals from body

3-10g daily

immune-system-support

Rich in nutrients that support immune function

3-6g daily

nutritional-deficiency-vegetarians

Complete protein and B12 source for plant-based diets

3-10g daily

environmental-toxin-exposure

Helps eliminate environmental toxins and pollutants

5-10g daily

energy-fatigue-support

Rich in energy-supporting nutrients and chlorophyll

3-6g daily

Where to buy it

compare forms first

Look for Chlorella at 3-10g per serving. The form that matters here is Cracked Cell Wall Chlorella.

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What else affects it

Beyond other supplements

Coffee tea tannins

Tannins may reduce mineral absorption

Tannins bind minerals reducing bioavailability

How it works

Cell wall components bind heavy metals and toxins for elimination
Rich in chlorophyll providing antioxidant and detox support
Complete protein supports tissue repair and immune function
High vitamin and mineral content supports multiple body systems
Growth factors may promote cellular repair and regeneration
Prebiotic effects support beneficial gut bacteria

Key findings

what the evidence supports

Good evidence for heavy metal detoxification and nutritional support
May support immune function and energy levels
Generally safe but start slowly to avoid detox reactions
Cracked cell wall forms have better bioavailability

Sources: NIH Examine.com · data reviewed 2026-08-02

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Chlorella?

Documented effects: Heavy metal detoxification; Enhanced immune system function; Complete nutritional support; Improved energy and vitality. Binds and removes heavy metals and toxins from the body

How much Chlorella should you take per day?

The common daily range is 3-10g. By goal — nutritional support: 3-6g daily; detoxification: 5-10g daily; heavy metal chelation: 10-20g daily; immune support: 3-6g daily.

When is the best time to take Chlorella?

With meals. First effects are typically reported within 1-2 weeks for energy and nutritional benefits.

What are the side effects of Chlorella?

At excessive doses: Generally safe but potential reactions:, Initial digestive upset and nausea, Temporary detox symptoms (headaches, fatigue), Possible iodine sensitivity in thyroid disorders, Rare allergic reactions. Safety rating at normal doses is 8 out of 10.

What should you not take with Chlorella?

Separate it from Medications Taken Together, Coffee Tea Tannins by two to four hours. May bind some medications reducing absorption

Does Chlorella interact with medications?

Documented interactions with blood-thinners, immunosuppressants, thyroid-medications. Discuss these with a pharmacist before combining.

How do you know if you need Chlorella?

The marker is Heavy metal levels or nutritional status markers, optimal range Reduced heavy metal levels and improved nutritional markers. Common deficiency signs: Poor detoxification capacity and toxin accumulation, Nutritional deficiencies especially B vitamins and protein, Compromised immune function and frequent infections, Low energy and chronic fatigue.

Taken for

49 Liver & Detox

Turmeric · Vitamin C (Ascorbic Acid) · D-Mannose