Liver detoxification support
Traditional support for liver detoxification and hepatic cleansing processes
Yellow Dock
Traditional liver and blood purifying herb with gentle laxative properties, supporting liver detoxification and skin health
Scientific nameRumex crispus
FormulaVarious anthraquinones and tannins
Molecular weightVariable natural compounds g/mol
CASVarious natural compounds
55
absorption score
6
safety / 10
25
USD per month
5
documented interactions
Check it against something
Yellow Dock with:
- Amylase
- Ashwagandha
- Avocado Oil
- BCAA (Branched-Chain Amino Acids)
- Beetroot Powder
- Beta-Alanine
- Bifidobacterium lactis
- Bifidobacterium longum
- Bovine Collagen
- Caffeine
- Calcium
- Calcium Bone Formula
- Calcium Carbonate
- Casein Protein
- Chicken Collagen
- Choline (Bitartrate)
- Chondroitin Sulfate
- Coconut Oil
- Collagen Peptides
- Comprehensive Immune Support Complex
- Comprehensive Multivitamin-Mineral Complex
- Creatine HCL
- Creatine Monohydrate
- D-Mannose
- Dandelion Root
- DHA
- Electrolyte Blend
- EPA
- Fish Oil (EPA/DHA)
- Folate (5-MTHF)
- Ginger
- Iron Fumarate
- Iron Sulfate
- Joint Mobility Formula
- Keratin
- Krill Oil
- L-Carnitine
- L-Citrulline
- Lactase
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lipase
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Oxide
- Marine Collagen
- Melatonin
- Modafinil
- Olive Oil Extract
- Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
- Papain
- Protease
- Saccharomyces boulardii
- Turmeric
- Vitamin B12 (Cyanocobalamin)
- Vitamin B12 (Methylcobalamin)
- Vitamin C (Ascorbic Acid)
- Vitamin C (Sodium Ascorbate)
- Vitamin D3
- Whey Protein
- Zinc Gluconate
Nothing found
75
out of 100
Works better together
Take together — same timing window amplifies the synergy.
What it does
mechanism and evidence for each claimBlood purification and cleansing
Traditional blood purifier supporting elimination of metabolic waste
Skin health through detoxification
Supports clear skin through liver and blood purification
Gentle bowel regulation
Provides gentle laxative support for regular bowel movements
Iron and mineral support
Good source of iron and minerals supporting energy and vitality
Others take these for the same thing
Same goal, different mechanism — check any of them against this one
Turmeric
Anti-inflammatory & antioxidant
300-1000mg
A
3%
Glutathione
Master antioxidant & detox support
250-750mg
B
20%
Astaxanthin
Superior antioxidant & skin protection
4-12mg
B
20%
SAM-e
Mood support & liver health
400-800mg
A
70%
Plant Collagen
Vegan collagen support & antioxidants
2-5g
C
70%
Quercetin
Immune support & allergy relief
500-1000mg
B
5%
Every pair we checked
12 combinations scored by the engine
Yellow Dock + Calcium Carbonate
High calcium may reduce iron absorption from yellow dock
Needs attention
52
Yellow Dock + Caffeine
No documented interaction either way
No known interaction
70
Yellow Dock + Creatine Monohydrate
No documented interaction either way
No known interaction
70
Yellow Dock + Whey Protein
No documented interaction either way
No known interaction
70
Yellow Dock + Lactase
No documented interaction either way
No known interaction
70
Yellow Dock + Bovine Collagen
No documented interaction either way
No known interaction
70
Yellow Dock + DHA
No documented interaction either way
No known interaction
70
Yellow Dock + Turmeric
No documented interaction either way
No known interaction
70
Yellow Dock + Fish Oil (EPA/DHA)
No documented interaction either way
No known interaction
70
Yellow Dock + Dandelion Root
Enhanced liver detoxification and cleansing support
Works better together
75
Yellow Dock + Vitamin D3
Enhanced iron absorption from yellow dock
Works better together
78
Yellow Dock + Burdock Root
Synergistic blood purification and skin health support
Works better together
80
Dosage
Daily300-600mg
Liver detoxification300-600mg daily
Blood purification300-500mg daily
Constipation relief200-400mg as needed
Iron support400-800mg daily
Before you take it
VeganYes
When to expect it
First Effects6-24 hours for laxative effects, 2-4 weeks for liver benefits
Peak Benefits6-12 weeks for sustained liver support and blood purification
Deficiency DevelopmentNot applicable - herbal supplement
Toxicity OnsetPossible with high doses or prolonged use
How to measure it
MarkerIron studies, liver enzymes, kidney function if long-term use
OptimalImproved iron status, normal liver and kidney function
Deficient belowNot applicable for herbal supplement
FrequencyEvery 6-12 months if using regularly
What people actually reported to the FDA
CAERS, 1 reports naming it as the suspectMost reported effects
Excluded from the list above: foreign body trauma (1). Those are people struggling with the tablet itself, not with the compound.
Named as the suspect
1 reports
of 2 that mention it at all
Serious outcome
67%
hospitalisation, emergency room or worse
Life Threatening1
Hospitalization1
Required Intervention1
Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →
What actually reaches you
The label counts the carrier, your body does not
Absorption
Moderate 55 of 100 · middle of the range for this compound
Delivered daily
247.5 mg
Cost per 100 mg delivered
$0.34 comparative — uses the absorption score, not a measured percentage
Works better with
+
Dandelion Root
Enhanced liver detoxification and cleansing support
Both provide liver-supportive and detoxification properties · level C
+
Burdock Root
Synergistic blood purification and skin health support
Both traditional blood purifiers with complementary actions · level C
+
Vitamin C
Enhanced iron absorption from yellow dock
Vitamin C improves absorption of plant-based iron · level BWhat not to take with Yellow Dock
!
Calcium Supplements High
High calcium may reduce iron absorption from yellow dock
Calcium can interfere with iron absorption · moderate significance
!
Antidiarrheal Medications
Opposes yellow dock's laxative effects
Direct opposition of bowel-stimulating effects · moderate significanceMedication interactions
Discuss these with a pharmacist before combiningHigh vitamin K content may affect anticoagulation
What to do: Monitor INR if on warfarin
May affect blood sugar levels
What to do: Monitor blood glucose levels
May enhance diuretic effects
What to do: Monitor fluid and electrolyte status
Available forms
Yellow Dock Root Extract: Traditional liver support, Blood purification, Iron source, Gentle laxative
Food sources
Young yellow dock leaves
High vitamins and minerals · 60
Yellow dock root tea
Moderate active compound content · 45
Standardized root extracts
Concentrated active compounds · 55
Not found in common foods
Specific plant preparation required · N/A
Too little
- Not applicable (herbal supplement, not essential nutrient):
- General symptoms addressed by yellow dock:
- Poor liver detoxification and sluggish hepatic function
- Skin problems related to poor elimination
- Chronic constipation and irregular bowel movements
- Iron deficiency and low energy levels
- General feeling of being 'toxic' or sluggish
Too much
- Potential concerns with high doses or prolonged use:
- Severe diarrhea and abdominal cramping
- Kidney stone formation due to high oxalates
- Nausea and digestive distress
- Electrolyte imbalances from excessive laxative use
- Liver irritation with very high doses
Who benefits most
liver-detoxification-support
Traditional liver cleanser supporting hepatic detoxification processes
300-600mg daily
skin-health-acne-eczema
Blood purification support for skin conditions and complexion
300-500mg daily
constipation-gentle-relief
Gentle natural laxative for occasional constipation relief
200-400mg as needed
iron-deficiency-anemia
Natural iron source for addressing iron deficiency and low energy
400-800mg daily
seasonal-blood-cleansing
Traditional spring blood purification and seasonal detoxification
300-600mg daily for 6-8 weeksWhere to buy it
Look for Yellow Dock at 300-600mg per serving. The form that matters here is Yellow Dock Root Extract.
Find on Amazon
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How it works
- Bitter compounds stimulate liver metabolism and detoxification pathways
- Anthraquinones provide gentle stimulant laxative effects
- High iron content supports hemoglobin production and energy
- Traditional blood purification through enhanced elimination
- Liver support improves skin health by reducing toxin burden
- Diuretic properties support kidney function and fluid elimination
Key findings
what the evidence supports- Strong traditional use evidence for liver and blood purification
- Good iron content confirmed in nutritional analysis
- Caution needed due to high oxalate content and kidney stone risk
- Limited modern clinical research on traditional uses
Sources: NIH Examine.com · data reviewed 2026-08-02
Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →
Common questions
What are the benefits of Yellow Dock?
Documented effects: Liver detoxification support; Blood purification and cleansing; Skin health through detoxification; Gentle bowel regulation. Traditional support for liver detoxification and hepatic cleansing processes
How much Yellow Dock should you take per day?
The common daily range is 300-600mg. By goal — liver detoxification: 300-600mg daily; blood purification: 300-500mg daily; constipation relief: 200-400mg as needed; iron support: 400-800mg daily.
When is the best time to take Yellow Dock?
With meals. First effects are typically reported within 6-24 hours for laxative effects, 2-4 weeks for liver benefits.
What are the side effects of Yellow Dock?
At excessive doses: Potential concerns with high doses or prolonged use:, Severe diarrhea and abdominal cramping, Kidney stone formation due to high oxalates, Nausea and digestive distress, Electrolyte imbalances from excessive laxative use. Safety rating at normal doses is 6 out of 10.
What should you not take with Yellow Dock?
Separate it from Calcium Supplements High, Antidiarrheal Medications by two to four hours. High calcium may reduce iron absorption from yellow dock
Does Yellow Dock interact with medications?
Documented interactions with blood-thinners, diabetes-medications, diuretic-medications. Discuss these with a pharmacist before combining.
How do you know if you need Yellow Dock?
The marker is Iron studies, liver enzymes, kidney function if long-term use, optimal range Improved iron status, normal liver and kidney function. Common deficiency signs: Not applicable (herbal supplement, not essential nutrient):, General symptoms addressed by yellow dock:, Poor liver detoxification and sluggish hepatic function, Skin problems related to poor elimination.