Hair health and growth
Supports healthy hair growth and prevents hair loss
Vitamin B7 (Biotin)
Essential B vitamin critical for hair, skin, nail health, and carbohydrate metabolism
Scientific nameBiotin
FormulaC10H16N2O3S
Molecular weight244.31 g/mol
CAS58-85-5
80
absorption score
10
safety / 10
15
USD per month
6
documented interactions
Check it against something
Vitamin B7 (Biotin) with:
- Amylase
- Ashwagandha
- Avocado Oil
- BCAA (Branched-Chain Amino Acids)
- Beetroot Powder
- Beta-Alanine
- Bifidobacterium lactis
- Bifidobacterium longum
- Bovine Collagen
- Caffeine
- Calcium
- Calcium Bone Formula
- Calcium Carbonate
- Casein Protein
- Chicken Collagen
- Choline (Bitartrate)
- Chondroitin Sulfate
- Coconut Oil
- Collagen Peptides
- Comprehensive Immune Support Complex
- Comprehensive Multivitamin-Mineral Complex
- Creatine HCL
- Creatine Monohydrate
- D-Mannose
- DHA
- Electrolyte Blend
- EPA
- Fish Oil (EPA/DHA)
- Folate (5-MTHF)
- Ginger
- Iron Fumarate
- Iron Sulfate
- Joint Mobility Formula
- Keratin
- Krill Oil
- L-Carnitine
- L-Citrulline
- Lactase
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lipase
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Oxide
- Marine Collagen
- Melatonin
- Modafinil
- Olive Oil Extract
- Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
- Papain
- Protease
- Saccharomyces boulardii
- Turmeric
- Vitamin B12 (Cyanocobalamin)
- Vitamin B12 (Methylcobalamin)
- Vitamin C (Ascorbic Acid)
- Vitamin C (Sodium Ascorbate)
- Vitamin D3
- Whey Protein
- Zinc Gluconate
- Zinc Picolinate
Nothing found
99
out of 100
Works better together
Compatible. Timing differs, so follow each supplement's own window.
What it does
mechanism and evidence for each claimNail strengthening
Increases nail thickness and reduces brittleness by 25%
Skin health support
Maintains healthy skin and supports healing
Metabolism support
Essential cofactor for carbohydrate and fat metabolism
Blood sugar regulation
May help improve glucose metabolism
Others take these for the same thing
Same goal, different mechanism — check any of them against this one
Collagen Peptides
Skin health & joint support
5-15g
B
85%
Bone Broth Collagen
Gut healing & collagen support
20-40g powder
B
85%
Vitamin B3 (Niacinamide)
Energy & skin health (no flush)
100-1000 mg
A
88%
Marine Collagen
Anti-aging & skin health
5-15g
A
95%
Astaxanthin
Superior antioxidant & skin protection
4-12mg
B
20%
Glycine
Sleep quality & collagen support
3-10g
A
95%
Every pair we checked
12 combinations scored by the engine
Vitamin B7 (Biotin) + Caffeine
No documented interaction either way
No known interaction
70
Vitamin B7 (Biotin) + Creatine Monohydrate
No documented interaction either way
No known interaction
70
Vitamin B7 (Biotin) + Whey Protein
No documented interaction either way
No known interaction
70
Vitamin B7 (Biotin) + Turmeric
No documented interaction either way
No known interaction
70
Vitamin B7 (Biotin) + Lactase
Improved calcium absorption when consuming dairy
Works better together
82
Vitamin B7 (Biotin) + Bovine Collagen
Essential for collagen synthesis and cross-linking
Works better together
82
Vitamin B7 (Biotin) + DHA
Prevents oxidation of DHA and enhances stability
Works better together
82
Vitamin B7 (Biotin) + Magnesium Oxide
Magnesium required for vitamin D metabolism
Works better together
82
Vitamin B7 (Biotin) + Vitamin D3
Both support collagen and keratin synthesis
Works better together
86
Vitamin B7 (Biotin) + Fish Oil (EPA/DHA)
Protects fish oil from oxidation
Works better together
90
Vitamin B7 (Biotin) + Calcium Carbonate
Essential for calcium absorption and utilization
Works better together
94
Vitamin B7 (Biotin) + Zinc Gluconate
Both important for hair and skin health
Works better together
99
Dosage
Daily300-5000 mcg
Maintenance30-100 mcg
Therapeutic2500-10000 mcg
Nail strengthening2500-5000 mcg
MaximumNo established upper limit
Before you take it
VeganYes
When to expect it
First Effects4-6 weeks for metabolic improvements
Peak Benefits6-12 months for hair and nail improvements
Deficiency Development3-4 weeks with biotin antagonists
Toxicity OnsetNo known toxicity at any dose
How to measure it
MarkerPlasma biotin concentration
Optimal200-1000 ng/L
Deficient below100 ng/L
FrequencyOnly if deficiency suspected or high-risk conditions
What people actually reported to the FDA
CAERS, 0 reports naming it as the suspect
Named as the suspect
0 reports
of 1 that mention it at all
Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →
What actually reaches you
The label counts the carrier, your body does not
Absorption
Very high 80 of 100 · best absorbed form of this compound
Delivered daily
2.1 mg
Cost per 10 mg delivered
$2.36 comparative — uses the absorption score, not a measured percentage
Works better with
+
Other B Vitamins
Work together in metabolic pathways
Complementary roles in energy metabolism · level A
+
Zinc
Both important for hair and skin health
Complementary roles in protein synthesis · level B
+
Vitamin C
Both support collagen and keratin synthesis
Complementary roles in structural protein formation · level BWhat not to take with Vitamin B7 (Biotin)
!
Raw Egg Whites
Avidin protein binds and inactivates biotin
Irreversible binding preventing absorption · major significance
!
Alcohol Chronic
Impairs biotin absorption and metabolism
Interferes with biotin transport and utilization · moderate significance
!
Alpha Lipoic Acid Megadoses
High doses may compete with biotin
Structural similarity may cause competition · mild significanceMedication interactions
Discuss these with a pharmacist before combiningIncreases biotin metabolism and requirements
What to do: Consider biotin supplementation
May reduce biotin-producing gut bacteria
What to do: Consider biotin supplementation during extended use
Available forms
D-Biotin: Natural active form, Well-absorbed, Most research
Biotin with Keratin: Synergistic for hair/nails, Enhanced effects, Targeted benefits
Food sources
Beef liver
31 mcg/100g · 85
Egg yolks (cooked)
25 mcg/100g · 80
Almonds
1.5 mcg/100g · 75
Sweet potato
2.4 mcg/100g · 70
Spinach
2.0 mcg/100g · 65
Too little
- Hair loss and thinning hair
- Brittle, splitting nails
- Scaly skin rash (especially around eyes, nose, mouth)
- Depression and lethargy
- Hallucinations (severe deficiency)
- Muscle pain and weakness
- Increased susceptibility to infections
Too much
- No known toxicity symptoms
- Possible interference with laboratory tests
- Mild digestive upset at extreme doses
- No upper limit established
- Excess excreted in urine
Who benefits most
brittle-nail-sufferers
Biotin significantly strengthens brittle nails
2500-5000 mcg daily
hair-loss-concerns
May support hair growth in deficient individuals
5000-10000 mcg daily
pregnant-women
Increased biotin requirements during pregnancy
30-35 mcg daily (higher if deficient)
anticonvulsant-users
These medications can cause biotin deficiency
300-5000 mcg daily
raw-egg-consumers
Raw egg whites contain biotin-binding avidin
300-1000 mcg dailyWhere to buy it
Look for Vitamin B7 (Biotin) at 300-5000 mcg per serving. The form that matters here is D-Biotin.
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What else affects it
Beyond other supplements
!
Alcohol chronic
Impairs biotin absorption and metabolism
Interferes with biotin transport and utilizationHow it works
- Cofactor for carboxylase enzymes in metabolism
- Required for fatty acid synthesis
- Essential for amino acid catabolism
- Critical for gluconeogenesis pathway
- Required for gene regulation and histone modification
- Essential for keratin production in hair and nails
Key findings
what the evidence supports- Increases nail thickness by 25% in brittle nail syndrome (Cutis 1993)
- Essential for carboxylase enzyme function - established biochemistry
- May improve hair growth in biotin-deficient individuals
- Critical for fetal development during pregnancy (AJCN 2002)
Sources: NIH Examine.com · data reviewed 2026-08-02
Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →
Common questions
What are the benefits of Vitamin B7 (Biotin)?
Documented effects: Hair health and growth; Nail strengthening; Skin health support; Metabolism support. Supports healthy hair growth and prevents hair loss
How much Vitamin B7 (Biotin) should you take per day?
The common daily range is 300-5000 mcg. By goal — maintenance: 30-100 mcg; therapeutic: 2500-10000 mcg; nail strengthening: 2500-5000 mcg; maximum: No established upper limit.
When is the best time to take Vitamin B7 (Biotin)?
Anytime with food. First effects are typically reported within 4-6 weeks for metabolic improvements.
What are the side effects of Vitamin B7 (Biotin)?
At excessive doses: No known toxicity symptoms, Possible interference with laboratory tests, Mild digestive upset at extreme doses, No upper limit established, Excess excreted in urine. Safety rating at normal doses is 10 out of 10.
What should you not take with Vitamin B7 (Biotin)?
Separate it from Raw Egg Whites, Alcohol Chronic, Alpha Lipoic Acid Megadoses by two to four hours. Avidin protein binds and inactivates biotin
Does Vitamin B7 (Biotin) interact with medications?
Documented interactions with anticonvulsants, antibiotics-long-term. Discuss these with a pharmacist before combining.
How do you know if you need Vitamin B7 (Biotin)?
The marker is Plasma biotin concentration, optimal range 200-1000 ng/L. Common deficiency signs: Hair loss and thinning hair, Brittle, splitting nails, Scaly skin rash (especially around eyes, nose, mouth), Depression and lethargy.