Cardiovascular health and heart protection
Supports heart health and may reduce cardiovascular disease risk
Resveratrol
Powerful polyphenol antioxidant that supports cardiovascular health, longevity, and cellular protection against aging
Scientific name3,5,4'-trihydroxy-trans-stilbene
FormulaC14H12O3
Molecular weight228.24 g/mol
CAS501-36-0
3
absorption score
7
safety / 10
35
USD per month
5
documented interactions
Check it against something
Resveratrol with:
- Amylase
- Ashwagandha
- Avocado Oil
- BCAA (Branched-Chain Amino Acids)
- Beetroot Powder
- Beta-Alanine
- Bifidobacterium lactis
- Bifidobacterium longum
- Bovine Collagen
- Caffeine
- Calcium
- Calcium Bone Formula
- Calcium Carbonate
- Casein Protein
- Chicken Collagen
- Choline (Bitartrate)
- Chondroitin Sulfate
- Coconut Oil
- Collagen Peptides
- Comprehensive Immune Support Complex
- Comprehensive Multivitamin-Mineral Complex
- Creatine HCL
- Creatine Monohydrate
- D-Mannose
- DHA
- Electrolyte Blend
- EPA
- Fish Oil (EPA/DHA)
- Folate (5-MTHF)
- Ginger
- Iron Fumarate
- Iron Sulfate
- Joint Mobility Formula
- Keratin
- Krill Oil
- L-Carnitine
- L-Citrulline
- Lactase
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lipase
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Oxide
- Marine Collagen
- Melatonin
- Modafinil
- Olive Oil Extract
- Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
- Papain
- Protease
- Quercetin
- Saccharomyces boulardii
- Turmeric
- Vitamin B12 (Cyanocobalamin)
- Vitamin B12 (Methylcobalamin)
- Vitamin C (Ascorbic Acid)
- Vitamin C (Sodium Ascorbate)
- Vitamin D3
- Whey Protein
- Zinc Gluconate
Nothing found
78
out of 100
Works better together
Take together — same timing window amplifies the synergy.
What it does
mechanism and evidence for each claimAnti-aging and longevity support
May activate longevity pathways and slow cellular aging
Powerful antioxidant protection
Protects cells from oxidative stress and free radical damage
Brain health and neuroprotection
May protect brain function and support cognitive health
Blood sugar and metabolic support
May improve insulin sensitivity and glucose metabolism
Others take these for the same thing
Same goal, different mechanism — check any of them against this one
Coenzyme Q10 (CoQ10)
Heart health & cellular energy
100-200mg
A
10%
Fish Oil (EPA/DHA)
Heart & brain health
1-2g EPA/DHA
A
85%
Collagen Peptides
Skin health & joint support
5-15g
B
85%
Bone Broth Collagen
Gut healing & collagen support
20-40g powder
B
85%
Vitamin B7 (Biotin)
Hair, skin & nail health
300-5000 mcg
A
80%
Vitamin B3 (Niacinamide)
Energy & skin health (no flush)
100-1000 mg
A
88%
Every pair we checked
12 combinations scored by the engine
Resveratrol + Caffeine
No documented interaction either way
No known interaction
70
Resveratrol + Creatine Monohydrate
No documented interaction either way
No known interaction
70
Resveratrol + Vitamin D3
No documented interaction either way
No known interaction
70
Resveratrol + Calcium Carbonate
No documented interaction either way
No known interaction
70
Resveratrol + Whey Protein
No documented interaction either way
No known interaction
70
Resveratrol + Lactase
No documented interaction either way
No known interaction
70
Resveratrol + Bovine Collagen
No documented interaction either way
No known interaction
70
Resveratrol + DHA
No documented interaction either way
No known interaction
70
Resveratrol + Turmeric
No documented interaction either way
No known interaction
70
Resveratrol + Quercetin
Enhanced antioxidant and anti-inflammatory effects
Works better together
78
Resveratrol + Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
Enhanced cardiovascular and anti-inflammatory benefits
Works better together
78
Resveratrol + Coenzyme Q10 (CoQ10)
Enhanced cardiovascular and mitochondrial benefits
Works better together
78
Dosage
Daily100-500mg
Cardiovascular health100-500mg daily
Anti aging250-500mg daily
Antioxidant support100-300mg daily
Therapeutic500-1000mg daily
When to expect it
First Effects2-4 weeks for initial antioxidant and cardiovascular benefits
Peak Benefits8-16 weeks for sustained anti-aging and longevity benefits
Deficiency DevelopmentReturn to baseline aging processes
Toxicity OnsetRare, mainly digestive upset
How to measure it
MarkerCardiovascular markers (lipid panel, inflammation)
OptimalImproved lipid profile and reduced inflammation
Deficient belowNot applicable for supplement
FrequencyEvery 3-6 months for cardiovascular monitoring
What people actually reported to the FDA
CAERS, 102 reports naming it as the suspectMost reported effects
Named as the suspect
102 reports
of 142 that mention it at all
Serious outcome
79%
hospitalisation, emergency room or worse
Other Serious or Important Medical Event57
Hospitalization35
Visited a Health Care Provider27
Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →
What actually reaches you
The label counts the carrier, your body does not
Absorption
Very low 3 of 100 · little of the dose reaches the bloodstream
Measured
1% of the dose
PubMed 15333514
Reaches blood daily
3 mg
Cost per 10 mg absorbed
$3.89 vs $35/month on the label
Works better with
+
Quercetin
Enhanced antioxidant and anti-inflammatory effects
Both are polyphenols with complementary antioxidant pathways · level B
+
Omega 3 Fatty Acids
Enhanced cardiovascular and anti-inflammatory benefits
Complementary heart health and anti-inflammatory effects · level B
+
Coq10
Enhanced cardiovascular and mitochondrial benefits
Both support heart health through different pathways · level BWhat not to take with Resveratrol
!
Alcohol Excess
Excessive alcohol may counteract cardiovascular benefits
High alcohol increases oxidative stress and inflammation · moderate significance
!
Smoking
Smoking increases oxidative stress
Tobacco smoke overwhelms antioxidant capacity · major significanceMedication interactions
Discuss these with a pharmacist before combiningMay enhance anticoagulant effects
What to do: Monitor INR closely
May interfere with immunosuppressive effects
What to do: Monitor immune function
May interact with estrogen-based medications
What to do: Monitor hormonal effects
Available forms
Trans-Resveratrol: Anti-aging effects, Heart health, Antioxidant, Longevity research
Micronized Resveratrol: Better absorption, Enhanced bioavailability, Same benefits, Improved delivery
Food sources
Red wine
1-2mg per glass · 25
Red grapes (skin)
0.5-1mg per cup · 20
Dark berries (blueberries)
Small amounts · 20
Resveratrol supplements
50-1000mg per capsule · 30-50
Too little
- Accelerated cardiovascular aging
- Increased oxidative stress and cellular damage
- Poor endothelial function and circulation
- Faster cellular aging processes
- Increased inflammation and metabolic dysfunction
- Reduced longevity pathway activation
- Poor adaptation to cellular stress
Too much
- Generally safe but potential concerns:
- Stomach upset with high doses
- Mild estrogenic effects in sensitive individuals
- Increased bleeding risk with blood thinners
- Rare allergic reactions
Who benefits most
cardiovascular-heart-health
Excellent for heart health and cardiovascular protection
100-500mg daily
anti-aging-longevity
May activate longevity pathways and slow cellular aging
250-500mg daily
antioxidant-support
Powerful antioxidant protection against cellular damage
100-300mg daily
metabolic-blood-sugar
May improve insulin sensitivity and glucose metabolism
150-300mg daily
brain-cognitive-health
May provide neuroprotection and support brain health
200-400mg dailyWhere to buy it
Look for Resveratrol at 100-500mg per serving. The form that matters here is Trans-Resveratrol.
Find on Amazon
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What else affects it
Beyond other supplements
!
Alcohol excess
Excessive alcohol may counteract cardiovascular benefits
High alcohol increases oxidative stress and inflammation
!
Smoking
Smoking increases oxidative stress
Tobacco smoke overwhelms antioxidant capacityHow it works
- Activates SIRT1 and other sirtuins promoting longevity pathways
- Improves endothelial function and nitric oxide production
- Direct antioxidant activity scavenging free radicals
- Anti-inflammatory effects reducing chronic inflammation
- Mimics beneficial effects of caloric restriction
- May activate AMPK pathway improving metabolic function
Key findings
what the evidence supports- Promising evidence for cardiovascular health and anti-aging
- Strong antioxidant effects but limited human longevity data
- Poor bioavailability limits effectiveness
- Generally safe with mild side effects
Sources: NIH Examine.com · data reviewed 2026-08-02
Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →
Common questions
What are the benefits of Resveratrol?
Documented effects: Cardiovascular health and heart protection; Anti-aging and longevity support; Powerful antioxidant protection; Brain health and neuroprotection. Supports heart health and may reduce cardiovascular disease risk
How much Resveratrol should you take per day?
The common daily range is 100-500mg. By goal — cardiovascular health: 100-500mg daily; anti aging: 250-500mg daily; antioxidant support: 100-300mg daily; therapeutic: 500-1000mg daily.
When is the best time to take Resveratrol?
With meals. First effects are typically reported within 2-4 weeks for initial antioxidant and cardiovascular benefits.
What are the side effects of Resveratrol?
At excessive doses: Generally safe but potential concerns:, Stomach upset with high doses, Mild estrogenic effects in sensitive individuals, Increased bleeding risk with blood thinners, Rare allergic reactions. Safety rating at normal doses is 7 out of 10.
What should you not take with Resveratrol?
Separate it from Alcohol Excess, Smoking by two to four hours. Excessive alcohol may counteract cardiovascular benefits
Does Resveratrol interact with medications?
Documented interactions with blood-thinners-warfarin, immunosuppressants, hormone-medications. Discuss these with a pharmacist before combining.
How do you know if you need Resveratrol?
The marker is Cardiovascular markers (lipid panel, inflammation), optimal range Improved lipid profile and reduced inflammation. Common deficiency signs: Accelerated cardiovascular aging, Increased oxidative stress and cellular damage, Poor endothelial function and circulation, Faster cellular aging processes.