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Pterostilbene-Resveratrol Anti-Aging and Longevity Complex

Potent combination of advanced stilbene compounds that activate longevity pathways, provide cellular protection, and support healthy aging processes

Scientific namePterostilbene + trans-Resveratrol synergistic combination FormulaPterostilbene: C16H16O3, Resveratrol: C14H12O3 Molecular weightPterostilbene: 256.30 g/mol, Resveratrol: 228.24 g/mol g/mol CASPterostilbene: 537-42-8, Resveratrol: 501-36-0
75 absorption score
8 safety / 10
80 USD per month
5 documented interactions

Check it against something

Evidence level B

Pterostilbene-Resveratrol Anti-Aging and Longevity Complex with:

Compatibility score 78 out of 100
78 out of 100
Works better together Take together — same timing window amplifies the synergy.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Powerful anti-aging and longevity support

Activates longevity pathways and slows cellular aging processes

Both compounds activate sirtuins and longevity genes Evidence B-grade 8-24 weeks

Enhanced cardiovascular health and protection

Supports heart health and vascular function

Improves endothelial function and reduces cardiovascular inflammation Evidence A-grade 6-16 weeks

Superior antioxidant protection and cellular defense

Provides powerful protection against oxidative stress

Both compounds neutralize free radicals and enhance cellular antioxidant systems Evidence A-grade 2-8 weeks

Improved cognitive function and neuroprotection

Supports brain health and cognitive performance

Crosses blood-brain barrier providing neuroprotective effects Evidence B-grade 8-16 weeks

Enhanced metabolic health and glucose regulation

Improves insulin sensitivity and metabolic function

Activates metabolic pathways and improves glucose metabolism Evidence B-grade 6-12 weeks

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Every pair we checked

12 combinations scored by the engine
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Caffeine No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Creatine Monohydrate No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Vitamin D3 No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Calcium Carbonate No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Whey Protein No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Lactase No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Bovine Collagen No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + DHA No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Turmeric No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Fish Oil (EPA/DHA) No documented interaction either way No known interaction 70
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Quercetin Enhanced antioxidant and anti-inflammatory effects Works better together 78
Pterostilbene-Resveratrol Anti-Aging and Longevity Complex + Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula Synergistic anti-inflammatory and longevity benefits Works better together 78

Dosage

With meals
Daily100-200mg pterostilbene + 250-500mg resveratrol
Anti aging longevity100-200mg pterostilbene + 250-500mg resveratrol daily
Cardiovascular support50-100mg pterostilbene + 200-400mg resveratrol daily
Cognitive protection100-150mg pterostilbene + 250-500mg resveratrol daily
Maximum therapeutic200mg pterostilbene + 1000mg resveratrol daily

When to expect it

First Effects2-4 weeks for antioxidant and cardiovascular benefits
Peak Benefits8-24 weeks for anti-aging and longevity effects
Deficiency DevelopmentNot essential nutrients - benefits from regular intake
Toxicity OnsetGenerally very safe - mild side effects possible

How to measure it

$200-300
MarkerOxidative stress markers, inflammatory markers, cardiovascular risk factors
OptimalReduced oxidative stress, improved cardiovascular markers
Deficient belowHigh oxidative stress, poor cardiovascular markers
FrequencyEvery 6-12 months for anti-aging monitoring

What actually reaches you

The label counts the carrier, your body does not
Absorption High 75 of 100 · absorbs well relative to other forms
Delivered daily 196.9 mg
Cost per 100 mg delivered $1.35 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented
+
Quercetin

Enhanced antioxidant and anti-inflammatory effects

Complementary polyphenol pathways and cellular protection · level B
+
Curcumin

Synergistic anti-inflammatory and longevity benefits

Both activate similar cellular protection pathways · level B
+
Nmn Nad Precursors

Enhanced cellular energy and longevity pathway activation

Both support cellular energy and repair mechanisms · level B

What not to take with Pterostilbene-Resveratrol Anti-Aging and Longevity Complex

2 documented
!
Excessive Alcohol

Alcohol may counteract longevity and health benefits

Oxidative stress and cellular damage from alcohol · moderate significance
!
High Sugar Diet

High glucose may interfere with metabolic benefits

Advanced glycation and inflammatory effects · moderate significance

Medication interactions

Discuss these with a pharmacist before combining
blood-thinning-medications Moderate

May enhance anticoagulant effects

What to do: Monitor bleeding parameters and INR

diabetes-medications Minor

May enhance blood sugar lowering effects

What to do: Monitor blood glucose levels

immunosuppressants Minor

May modulate immune function

What to do: Monitor immune function

Available forms

bioavailability compared
Pterostilbene-Resveratrol Complex 75
Separate High-Quality Compounds 70
Micronized Particle Formula 85

Pterostilbene-Resveratrol Complex: Optimized ratios, Synergistic effects, Convenient, Research-backed

Separate High-Quality Compounds: Customizable doses, Pure compounds, Flexibility, Quality control

Micronized Particle Formula: Enhanced absorption, Better bioavailability, Faster effects, Advanced technology

Food sources

before you supplement
Blueberries and berries Small amounts of pterostilbene, natural antioxidants · 40
Red wine and grapes Resveratrol source, variable concentrations · 30
Standardized stilbene complex 100-200mg pterostilbene + 250-500mg resveratrol · 75

Too little

deficiency signs
  • Antioxidant support deficiency symptoms:
  • Accelerated aging and cellular damage
  • Increased oxidative stress and inflammation
  • Poor cardiovascular health markers
  • Cognitive decline and brain fog
  • Reduced cellular energy and vitality
  • Increased susceptibility to age-related diseases

Too much

toxicity signs
  • Stilbene excess symptoms (rare):
  • Digestive upset and nausea
  • Headaches in sensitive individuals
  • Mild hormonal effects
  • Drug interaction effects
  • Allergic reactions (rare)
  • Sleep disruption with high doses

Who benefits most

aging-adults-longevity-focused

Primary compounds for anti-aging and longevity support

100-200mg pterostilbene + 250-500mg resveratrol daily
cardiovascular-health-support

Strong evidence for heart health and vascular protection

50-100mg pterostilbene + 200-400mg resveratrol daily
cognitive-health-neuroprotection

Brain-protective effects and cognitive enhancement

100-150mg pterostilbene + 250-500mg resveratrol daily
metabolic-health-diabetes-risk

Glucose regulation and metabolic benefits

100-200mg pterostilbene + 250-500mg resveratrol daily
antioxidant-cellular-protection

Superior antioxidant protection and cellular health

50-100mg pterostilbene + 200-400mg resveratrol daily

Where to buy it

compare forms first

Look for Pterostilbene-Resveratrol Anti-Aging and Longevity Complex at 100-200mg pterostilbene + 250-500mg resveratrol per serving. The form that matters here is Pterostilbene-Resveratrol Complex.

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What else affects it

Beyond other supplements
!
Excessive alcohol

Alcohol may counteract longevity and health benefits

Oxidative stress and cellular damage from alcohol
!
High sugar diet

High glucose may interfere with metabolic benefits

Advanced glycation and inflammatory effects

How it works

  • Activates sirtuins (SIRT1) longevity and cellular repair proteins
  • Enhances mitochondrial biogenesis and cellular energy production
  • Provides powerful antioxidant protection against oxidative stress
  • Improves endothelial function and cardiovascular health
  • Modulates inflammatory pathways and reduces chronic inflammation
  • Supports healthy gene expression and cellular stress resistance

Key findings

what the evidence supports
  • Strong cardiovascular protection and anti-aging benefits
  • Pterostilbene shows superior bioavailability to resveratrol
  • Combination may be more effective than individual compounds
  • Generally safe with minimal side effects

Sources: NIH Examine.com · data reviewed 2026-08-01

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Pterostilbene-Resveratrol Anti-Aging and Longevity Complex?

Documented effects: Powerful anti-aging and longevity support; Enhanced cardiovascular health and protection; Superior antioxidant protection and cellular defense; Improved cognitive function and neuroprotection. Activates longevity pathways and slows cellular aging processes

How much Pterostilbene-Resveratrol Anti-Aging and Longevity Complex should you take per day?

The common daily range is 100-200mg pterostilbene + 250-500mg resveratrol. By goal — anti aging longevity: 100-200mg pterostilbene + 250-500mg resveratrol daily; cardiovascular support: 50-100mg pterostilbene + 200-400mg resveratrol daily; cognitive protection: 100-150mg pterostilbene + 250-500mg resveratrol daily; maximum therapeutic: 200mg pterostilbene + 1000mg resveratrol daily.

When is the best time to take Pterostilbene-Resveratrol Anti-Aging and Longevity Complex?

With meals. First effects are typically reported within 2-4 weeks for antioxidant and cardiovascular benefits.

What are the side effects of Pterostilbene-Resveratrol Anti-Aging and Longevity Complex?

At excessive doses: Stilbene excess symptoms (rare):, Digestive upset and nausea, Headaches in sensitive individuals, Mild hormonal effects, Drug interaction effects. Safety rating at normal doses is 8 out of 10.

What should you not take with Pterostilbene-Resveratrol Anti-Aging and Longevity Complex?

Separate it from Excessive Alcohol, High Sugar Diet by two to four hours. Alcohol may counteract longevity and health benefits

Does Pterostilbene-Resveratrol Anti-Aging and Longevity Complex interact with medications?

Documented interactions with blood-thinning-medications, diabetes-medications, immunosuppressants. Discuss these with a pharmacist before combining.

How do you know if you need Pterostilbene-Resveratrol Anti-Aging and Longevity Complex?

The marker is Oxidative stress markers, inflammatory markers, cardiovascular risk factors, optimal range Reduced oxidative stress, improved cardiovascular markers. Common deficiency signs: Antioxidant support deficiency symptoms:, Accelerated aging and cellular damage, Increased oxidative stress and inflammation, Poor cardiovascular health markers.

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