Chamomile

Gentle anti-inflammatory and skin soothing herb with calming properties, supporting sensitive skin health and irritation relief

Scientific nameMatricaria chamomilla FormulaC15H20O (chamazulene) Molecular weight216.32 g/mol CAS529-05-5

65 absorption score

9 safety / 10

18 USD per month

4 documented interactions

Check it against something

Evidence level C

Chamomile with:

80 out of 100

Works better together Take together — same timing window amplifies the synergy.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Anti-inflammatory skin relief

Gentle anti-inflammatory support for skin inflammation and irritation

Chamazulene and bisabolol provide potent anti-inflammatory effects Evidence B-grade 30 minutes to 6 hours

Sensitive skin soothing

Calming support for sensitive, reactive, and easily irritated skin

Soothing compounds reduce skin sensitivity and provide comfort Evidence B-grade Minutes to hours

Eczema and dermatitis support

Traditional support for eczema, dermatitis, and inflammatory skin conditions

Anti-inflammatory and healing properties address skin condition symptoms Evidence B-grade 1-4 weeks

Wound healing and skin repair

Gentle support for minor wound healing and skin tissue repair

Anti-inflammatory effects and tissue-healing compounds promote recovery Evidence C-grade 3-14 days

Antimicrobial skin protection

Mild antimicrobial support protecting against skin infections

Antimicrobial compounds provide gentle protective effects Evidence C-grade 1-7 days

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Collagen Peptides Skin health & joint support 5-15g B 85% Bone Broth Collagen Gut healing & collagen support 20-40g powder B 85% Vitamin B7 (Biotin) Hair, skin & nail health 300-5000 mcg A 80% Vitamin B3 (Niacinamide) Energy & skin health (no flush) 100-1000 mg A 88% Marine Collagen Anti-aging & skin health 5-15g A 95% Astaxanthin Superior antioxidant & skin protection 4-12mg B 20%

Every pair we checked

12 combinations scored by the engine

Chamomile + Caffeine No documented interaction either way No known interaction 70

Chamomile + Creatine Monohydrate No documented interaction either way No known interaction 70

Chamomile + Vitamin D3 No documented interaction either way No known interaction 70

Chamomile + Calcium Carbonate No documented interaction either way No known interaction 70

Chamomile + Whey Protein No documented interaction either way No known interaction 70

Chamomile + Lactase No documented interaction either way No known interaction 70

Chamomile + Bovine Collagen No documented interaction either way No known interaction 70

Chamomile + DHA No documented interaction either way No known interaction 70

Chamomile + Turmeric No documented interaction either way No known interaction 70

Chamomile + Fish Oil (EPA/DHA) No documented interaction either way No known interaction 70

Chamomile + Aloe Vera Synergistic skin soothing and healing support Works better together 75

Chamomile + Calendula Enhanced anti-inflammatory and skin healing effects Works better together 80

Dosage

As needed topically

DailyTopical or 200-400mg oral

Topical sensitive skinApply 2-3 times daily to affected area

Topical inflammationApply 2-4 times daily as needed

Oral skin support200-400mg daily

Baby skin careDiluted topical application as needed

Before you take it

VeganYes

When to expect it

First EffectsMinutes to hours for soothing effects, 30 minutes to 6 hours for anti-inflammatory benefits

Peak Benefits1-4 weeks for sustained skin health and sensitivity reduction

Deficiency DevelopmentNot applicable - herbal supplement

Toxicity OnsetVery rare, excellent safety profile

How to measure it

Not typically necessary

MarkerGenerally not needed - assess through skin improvement

OptimalReduced skin sensitivity and inflammation

Deficient belowNot applicable for herbal supplement

FrequencyMonitor through skin health and sensitivity improvements

What people actually reported to the FDA

CAERS, 13 reports naming it as the suspect

Most reported effects

Fall 2

Nausea 2

Dizziness 2

Dyspnoea 1

Urticaria 1

Named as the suspect 13 reports of 32 that mention it at all

Serious outcome 90% hospitalisation, emergency room or worse

Other Serious or Important Medical Event12

Visited Emergency Room3

Visited a Health Care Provider2

Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →

What actually reaches you

The label counts the carrier, your body does not

Absorption High 65 of 100 · absorbs well relative to other forms

Delivered daily 195 mg

Cost per 100 mg delivered $0.31 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented

Calendula

Enhanced anti-inflammatory and skin healing effects

Both provide complementary anti-inflammatory and soothing effects · level C

Aloe Vera

Synergistic skin soothing and healing support

Both provide gentle skin healing and protective effects · level C

Oat Extract

Enhanced skin barrier support and soothing effects

Complementary skin barrier protection and sensitivity reduction · level C

What not to take with Chamomile

1 documented

Skin Irritating Substances

May not work as well with harsh skin irritants

Gentle soothing vs. strong irritating effects · minimal significance

Medication interactions

Discuss these with a pharmacist before combining

blood-thinners Minor

May have mild anticoagulant effects with high doses

What to do: Monitor if using large amounts orally

sedative-medications Minor

May enhance sedative effects with oral use

What to do: Monitor for increased sedation

topical-medications None

Generally compatible with topical treatments

What to do: Safe concurrent topical use

Available forms

bioavailability compared

Chamomile Extract (Standardized Chamazulene) 65

Chamomile Extract (Standardized Chamazulene): Excellent for sensitive skin, Very gentle and safe, Anti-inflammatory, Calming effects

Food sources

before you supplement

Chamomile tea Moderate active compound content · 50

Fresh chamomile flowers Natural compounds for topical use · 45

Chamomile essential oil (topical) Concentrated chamazulene and bisabolol · 75

Standardized extracts Concentrated active compounds · 65

Too little

deficiency signs

Not applicable (herbal supplement, not essential nutrient):
General symptoms addressed by chamomile:
Sensitive and easily irritated skin
Chronic skin inflammation and redness
Eczema and dermatitis flare-ups
Stress-related skin reactivity
Poor skin comfort and frequent irritation

Too much

toxicity signs

Extremely safe with minimal side effects:
Rare allergic reactions in sensitive individuals
Contact dermatitis in allergic individuals
Eye irritation if applied near eyes
Cross-reactivity with ragweed allergies

Who benefits most

sensitive-reactive-skin

Excellent gentle support for sensitive and easily reactive skin

Topical application 2-3 times daily

eczema-dermatitis-inflammation

Anti-inflammatory support for eczema, dermatitis, and skin inflammation

Topical application 2-4 times daily

skin-irritation-redness

Soothing relief for skin irritation, redness, and inflammation

Topical application as needed

baby-child-skin-care

Gentle skin care for babies and children with sensitive skin

Diluted topical application as needed

stress-related-skin-issues

Calming support for stress-related skin problems and sensitivity

Topical application or 200-400mg oral daily

Where to buy it

compare forms first

Look for Chamomile at Topical or 200-400mg oral per serving. The form that matters here is Chamomile Extract (Standardized Chamazulene).

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How it works

Chamazulene and bisabolol provide potent anti-inflammatory effects
Soothing compounds reduce skin sensitivity and provide immediate comfort
Anti-inflammatory properties address eczema and dermatitis symptoms
Gentle antimicrobial effects provide mild protective benefits
Calming effects may help stress-related skin issues
Promotes skin barrier function and reduces reactivity

Key findings

what the evidence supports

Strong evidence for anti-inflammatory skin effects
Good research on eczema and dermatitis support
Excellent safety profile, especially for sensitive skin
Extensive traditional use validation for skin conditions

Sources: NIH Examine.com · data reviewed 2026-08-02

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Chamomile?

Documented effects: Anti-inflammatory skin relief; Sensitive skin soothing; Eczema and dermatitis support; Wound healing and skin repair. Gentle anti-inflammatory support for skin inflammation and irritation

How much Chamomile should you take per day?

The common daily range is Topical or 200-400mg oral. By goal — topical sensitive skin: Apply 2-3 times daily to affected area; topical inflammation: Apply 2-4 times daily as needed; oral skin support: 200-400mg daily; baby skin care: Diluted topical application as needed.

When is the best time to take Chamomile?

As needed topically. First effects are typically reported within Minutes to hours for soothing effects, 30 minutes to 6 hours for anti-inflammatory benefits.

What are the side effects of Chamomile?

At excessive doses: Extremely safe with minimal side effects:, Rare allergic reactions in sensitive individuals, Contact dermatitis in allergic individuals, Eye irritation if applied near eyes, Cross-reactivity with ragweed allergies. Safety rating at normal doses is 9 out of 10.

What should you not take with Chamomile?

Separate it from Skin Irritating Substances by two to four hours. May not work as well with harsh skin irritants

Does Chamomile interact with medications?

Documented interactions with blood-thinners, sedative-medications, topical-medications. Discuss these with a pharmacist before combining.

How do you know if you need Chamomile?

The marker is Generally not needed - assess through skin improvement, optimal range Reduced skin sensitivity and inflammation. Common deficiency signs: Not applicable (herbal supplement, not essential nutrient):, General symptoms addressed by chamomile:, Sensitive and easily irritated skin, Chronic skin inflammation and redness.

Taken for

31 Skin & Hair

Bovine Collagen · Marine Collagen · Collagen Peptides