Check a pair

Burdock Root

Traditional blood purifying and liver supporting herb with prebiotic properties, used for skin health and detoxification

Scientific nameArctium lappa FormulaVarious inulin and phenolic compounds Molecular weightVariable natural compounds g/mol CASVarious natural compounds
60 absorption score
8 safety / 10
28 USD per month
4 documented interactions

Check it against something

Evidence level C

Burdock Root with:

Compatibility score 80 out of 100
80 out of 100
Works better together Take together — same timing window amplifies the synergy.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Blood purification and detoxification

Traditional blood purifier supporting elimination of metabolic waste and toxins

Supports liver and kidney elimination pathways for blood cleansing Evidence C-grade 4-8 weeks

Liver detoxification support

Supports liver's natural detoxification processes and hepatic function

Liver-supportive compounds enhance hepatic metabolism and detoxification Evidence C-grade 3-8 weeks

Skin health and complexion

Improves skin health and complexion through blood purification

Improved elimination reduces skin burden of toxin elimination Evidence C-grade 6-16 weeks

Prebiotic and digestive support

High inulin content provides prebiotic benefits for gut health

Inulin feeds beneficial gut bacteria supporting digestive health Evidence B-grade 2-6 weeks

Anti-inflammatory support

Provides natural anti-inflammatory benefits for various conditions

Phenolic compounds provide systemic anti-inflammatory effects Evidence C-grade 4-12 weeks

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Every pair we checked

12 combinations scored by the engine
Burdock Root + Caffeine No documented interaction either way No known interaction 70
Burdock Root + Creatine Monohydrate No documented interaction either way No known interaction 70
Burdock Root + Vitamin D3 No documented interaction either way No known interaction 70
Burdock Root + Calcium Carbonate No documented interaction either way No known interaction 70
Burdock Root + Whey Protein No documented interaction either way No known interaction 70
Burdock Root + Lactase No documented interaction either way No known interaction 70
Burdock Root + Bovine Collagen No documented interaction either way No known interaction 70
Burdock Root + DHA No documented interaction either way No known interaction 70
Burdock Root + Turmeric No documented interaction either way No known interaction 70
Burdock Root + Dandelion Root Comprehensive liver and detoxification support Works better together 75
Burdock Root + Lactobacillus acidophilus Enhanced digestive and gut health support Works better together 78
Burdock Root + Yellow Dock Enhanced blood purification and liver detoxification support Works better together 80

Dosage

With meals
Daily400-800mg
Blood purification400-800mg daily
Skin health400-600mg daily
Liver detoxification400-800mg daily
Prebiotic support500-1000mg daily

Before you take it

VeganYes

When to expect it

First Effects2-4 weeks for prebiotic benefits, 4-8 weeks for blood purification
Peak Benefits8-16 weeks for sustained blood purification and skin health
Deficiency DevelopmentNot applicable - herbal supplement
Toxicity OnsetVery rare, excellent safety profile

How to measure it

Not typically necessary
MarkerGenerally not needed - assess through symptom improvement
OptimalImproved skin health and digestive function
Deficient belowNot applicable for herbal supplement
FrequencyMonitor through skin and digestive health improvements

What people actually reported to the FDA

CAERS, 3 reports naming it as the suspect

Most reported effects

Diarrhoea 1
Malaise 1
Vomiting 1
Abdominal pain upper 1
Abdominal pain 1
Named as the suspect 3 reports of 5 that mention it at all
Serious outcome 60% hospitalisation, emergency room or worse
Hospitalization2
Visited a Health Care Provider2
Visited Emergency Room1

Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →

What actually reaches you

The label counts the carrier, your body does not
Absorption High 60 of 100 · absorbs well relative to other forms
Delivered daily 360 mg
Cost per 100 mg delivered $0.26 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented
+
Yellow Dock

Enhanced blood purification and liver detoxification support

Both traditional blood purifiers with complementary actions · level C
+
Dandelion Root

Comprehensive liver and detoxification support

Both provide liver-supportive and elimination-enhancing effects · level C
+
Probiotics

Enhanced digestive and gut health support

Burdock's inulin feeds beneficial bacteria while probiotics populate · level B

What not to take with Burdock Root

1 documented
!
Antibiotics Broad Spectrum

Antibiotics may reduce benefits of prebiotic inulin

Antibiotics kill beneficial bacteria that inulin feeds · mild significance

Medication interactions

Discuss these with a pharmacist before combining
diabetes-medications Minor

May affect blood sugar levels

What to do: Monitor blood glucose levels

blood-thinners Minor

Theoretical interaction due to potential anticoagulant effects

What to do: Monitor bleeding parameters

no-major-interactions None

Generally safe with most medications

What to do: Safe concurrent use

Available forms

bioavailability compared
Burdock Root Extract (Standardized Inulin) 60

Burdock Root Extract (Standardized Inulin): Excellent safety, Prebiotic benefits, Traditional use, Blood purification

Food sources

before you supplement
Fresh burdock root (gobo) High inulin and active compounds · 70
Burdock root tea Moderate active compound content · 50
Dried burdock root powder Concentrated compounds · 55
Standardized extracts Concentrated inulin and actives · 60

Too little

deficiency signs
  • Not applicable (herbal supplement, not essential nutrient):
  • General symptoms addressed by burdock root:
  • Poor blood purification and sluggish elimination
  • Skin problems related to poor detoxification
  • Poor gut health and digestive imbalances
  • Chronic inflammation and slow healing
  • General feeling of being 'toxic' or congested

Too much

toxicity signs
  • Extremely safe with minimal side effects:
  • Allergic reactions in sensitive individuals
  • Mild blood sugar effects
  • Digestive upset with high doses
  • Rare skin reactions

Who benefits most

blood-purification-detox

Traditional blood purifier supporting elimination and detoxification

400-800mg daily
skin-health-acne-eczema

Blood purification support for acne, eczema, and skin conditions

400-600mg daily
liver-detoxification-support

Supports liver detoxification and hepatic cleansing processes

400-800mg daily
digestive-health-prebiotic

High inulin content provides excellent prebiotic support for gut health

500-1000mg daily
anti-inflammatory-natural

Natural anti-inflammatory support for various inflammatory conditions

400-800mg daily

Where to buy it

compare forms first

Look for Burdock Root at 400-800mg per serving. The form that matters here is Burdock Root Extract (Standardized Inulin).

Find on Amazon

Affiliate link — we may earn a commission at no cost to you.

How it works

  • Supports liver and kidney elimination pathways for blood purification
  • High inulin content provides prebiotic benefits for beneficial gut bacteria
  • Phenolic compounds provide anti-inflammatory and antioxidant effects
  • Traditional blood cleansing through enhanced elimination processes
  • Liver-supportive compounds enhance hepatic detoxification
  • Diuretic properties support kidney function and toxin elimination

Key findings

what the evidence supports
  • Strong traditional use evidence for blood purification and skin health
  • Good research on prebiotic benefits of inulin content
  • Promising anti-inflammatory and antioxidant effects
  • Excellent safety profile with minimal side effects

Sources: NIH Examine.com · data reviewed 2026-08-02

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Burdock Root?

Documented effects: Blood purification and detoxification; Liver detoxification support; Skin health and complexion; Prebiotic and digestive support. Traditional blood purifier supporting elimination of metabolic waste and toxins

How much Burdock Root should you take per day?

The common daily range is 400-800mg. By goal — blood purification: 400-800mg daily; skin health: 400-600mg daily; liver detoxification: 400-800mg daily; prebiotic support: 500-1000mg daily.

When is the best time to take Burdock Root?

With meals. First effects are typically reported within 2-4 weeks for prebiotic benefits, 4-8 weeks for blood purification.

What are the side effects of Burdock Root?

At excessive doses: Extremely safe with minimal side effects:, Allergic reactions in sensitive individuals, Mild blood sugar effects, Digestive upset with high doses, Rare skin reactions. Safety rating at normal doses is 8 out of 10.

What should you not take with Burdock Root?

Separate it from Antibiotics Broad Spectrum by two to four hours. Antibiotics may reduce benefits of prebiotic inulin

Does Burdock Root interact with medications?

Documented interactions with diabetes-medications, blood-thinners, no-major-interactions. Discuss these with a pharmacist before combining.

How do you know if you need Burdock Root?

The marker is Generally not needed - assess through symptom improvement, optimal range Improved skin health and digestive function. Common deficiency signs: Not applicable (herbal supplement, not essential nutrient):, General symptoms addressed by burdock root:, Poor blood purification and sluggish elimination, Skin problems related to poor detoxification.

Taken for