Zinc Carnosine

Unique chelated complex of zinc and carnosine providing targeted gastric protection and healing

Scientific nameZinc L-Carnosine Complex FormulaC9H12N4O3Zn Molecular weight289.61 g/mol CAS107667-60-7

85 absorption score

8 safety / 10

35 USD per month

22 elemental zinc %

5 documented interactions

Check it against something

Evidence level B

Zinc Carnosine with:

86 out of 100

Works better together Compatible. Timing differs, so follow each supplement's own window.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Gastric mucosal protection

Protects and strengthens stomach lining against acid damage

Forms protective coating and supports mucus production Evidence A-grade 2-8 weeks

Accelerated ulcer healing

Speeds healing of gastric and duodenal ulcers significantly

Promotes tissue repair and reduces inflammation Evidence A-grade 4-12 weeks

Anti-inflammatory gastric effects

Reduces inflammation in stomach and duodenum

Inhibits inflammatory cytokines and oxidative stress Evidence A-grade 2-6 weeks

Enhanced gastric antioxidant activity

Increases antioxidant enzymes in gastric tissue

Zinc supports SOD and other antioxidant enzymes Evidence B-grade 4-8 weeks

Improved gastric emptying

May help normalize gastric motility and emptying

Supports normal gastric muscle function Evidence B-grade 4-8 weeks

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Probiotics for Autoimmune Disease Support Gut health & immune modulation 10-100 billion CFU daily B 60% Magnesium Glycinate Superior absorption sleep & muscle support 200-600 mg A 90% Magnesium Citrate Balanced absorption & digestive support 300-600 mg A 35% Chloride Electrolyte & digestive support 2300mg A 95% Bone Broth Collagen Gut healing & collagen support 20-40g powder B 85% Psyllium Husk Digestive health & cholesterol support 5-15g A 95%

Or a different form of the same thing

the comparison people search most

Zinc Carnosine vs Zinc Picolinate absorption 85 against 95 · $35 against $20 a month 95% Zinc Carnosine vs Zinc Gluconate absorption 85 against 60 · $35 against $20 a month 60% Zinc Carnosine vs Zinc Bisglycinate absorption 85 against 85 · $35 against $35 a month 85% Zinc Carnosine vs Zinc Citrate absorption 85 against 70 · $35 against $25 a month 70%

All Zinc forms ranked by absorption →

Every pair we checked

12 combinations scored by the engine

Zinc Carnosine + Iron Sulfate May reduce iron absorption Needs attention 52

Zinc Carnosine + Calcium Carbonate May reduce calcium absorption Needs attention 58

Zinc Carnosine + Caffeine No documented interaction either way No known interaction 70

Zinc Carnosine + Creatine Monohydrate No documented interaction either way No known interaction 70

Zinc Carnosine + Whey Protein No documented interaction either way No known interaction 70

Zinc Carnosine + Lactase No documented interaction either way No known interaction 70

Zinc Carnosine + Bovine Collagen No documented interaction either way No known interaction 70

Zinc Carnosine + DHA No documented interaction either way No known interaction 70

Zinc Carnosine + Turmeric No documented interaction either way No known interaction 70

Zinc Carnosine + Lactobacillus acidophilus Improved overall gastric and intestinal health Works better together 75

Zinc Carnosine + Vitamin D3 Enhanced antioxidant protection and tissue healing Works better together 86

Zinc Carnosine + Vitamin C (Ascorbic Acid) Enhanced antioxidant protection and tissue healing Works better together 86

Dosage

Empty stomach

Daily75-150mg twice daily

Gastric protection37.5-75mg daily

Therapeutic75-150mg twice daily

Ulcer healing75-150mg twice daily for 8-12 weeks

MaximumDo not exceed 300mg daily

Upper limit 40 mg NIH ODS

When to expect it

First Effects1-2 weeks for gastric comfort improvement

Peak Benefits8-12 weeks for optimal gastric healing and protection

Deficiency DevelopmentNot applicable - therapeutic supplement

Toxicity OnsetMonths of high-dose use for copper depletion

How to measure it

$80-120

MarkerZinc levels, copper levels, gastric function markers

OptimalAdequate zinc and copper balance

Deficient belowNot applicable for therapeutic supplement

FrequencyMonitor copper status with long-term use

What people actually reported to the FDA

CAERS, 517 reports naming it as the suspect

Most reported effects

Cough 44

Malaise 40

Vomiting 40

Nausea 38

Dyspnoea 36

Excluded from the list above: choking (76). Those are people struggling with the tablet itself, not with the compound.

Named as the suspect 517 reports of 964 that mention it at all

Serious outcome 87% hospitalisation, emergency room or worse

Other Serious or Important Medical Event398

Hospitalization81

Visited a Health Care Provider71

Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →

What actually reaches you

The label counts the carrier, your body does not

Elemental zinc 22.6% of 289.61 g/mol

Absorption Very high 85 of 100 · best absorbed form of this compound

Delivered daily 21.6 mg

Cost per 100 mg delivered $5.40 comparative — uses the absorption score, not a measured percentage

A 500 mg capsule of Zinc Carnosine contains 113 mg of zinc. How much of that crosses into your blood is not measured for this form — the absorption score ranks it against other forms, it is not a share of the dose. How this is calculated →

Works better with

3 documented

Vitamin C

Enhanced antioxidant protection and tissue healing

Synergistic antioxidant effects support gastric repair · level B

Vitamin A

Enhanced mucosal integrity and healing

Both support epithelial tissue health and repair · level B

Probiotics

Improved overall gastric and intestinal health

Complementary support for digestive ecosystem · level C

What not to take with Zinc Carnosine

2 documented

Iron Supplements

May reduce iron absorption

Zinc competes with iron for absorption · moderate significance

Calcium Supplements

May reduce calcium absorption

Mineral competition for absorption pathways · mild significance

Medication interactions

Discuss these with a pharmacist before combining

antibiotics-quinolones Moderate

May reduce antibiotic absorption

What to do: Separate dosing by 2-4 hours

tetracyclines Major

Significantly reduces antibiotic effectiveness

What to do: Separate dosing by 4-6 hours

proton-pump-inhibitors Minor

May reduce zinc absorption

What to do: Monitor for reduced effectiveness

Available forms

bioavailability compared

Ranks 3 of 5 among zinc forms. Zinc Picolinate absorbs better — 95%. Compare all forms →

Zinc L-Carnosine Complex (PepZin GI) 85

Zinc L-Carnosine Complex (PepZin GI): Clinically proven, Targeted delivery, Dual benefits, Superior to regular zinc

Food sources

before you supplement

Not found naturally as zinc-carnosine complex Must be obtained through supplementation · N/A

Zinc L-Carnosine supplements 37.5-150mg standardized complex · 85

Regular zinc + carnosine separately Less effective than chelated complex · 60

Pharmaceutical Polaprezinc Prescription form in some countries · 90

Too little

deficiency signs

Not applicable (therapeutic supplement, not essential nutrient):
Conditions addressed by zinc-carnosine:
Gastric ulcers and mucosal damage
Chronic gastritis and stomach inflammation
NSAID-induced gastric injury
H. pylori-related gastric problems
General gastric discomfort and irritation

Too much

toxicity signs

Generally safe but monitor for:
Copper deficiency with long-term high-dose use
Nausea and digestive upset
Reduced absorption of other minerals
Immune system suppression with excessive zinc

Who benefits most

gastric-ulcers

Clinically proven to accelerate ulcer healing

75-150mg twice daily on empty stomach

gastritis-stomach-inflammation

Reduces inflammation and protects gastric mucosa

75mg twice daily

nsaid-users

Protects against NSAID-induced gastric damage

75mg twice daily

h-pylori-support

May support gastric healing during H. pylori treatment

75-150mg twice daily

gastric-discomfort

General gastric protection and comfort

37.5-75mg daily

Where to buy it

compare forms first

Look for Zinc Carnosine at 75-150mg twice daily per serving. The form that matters here is Zinc L-Carnosine Complex (PepZin GI).

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How it works

Slow-release zinc directly targets gastric mucosa
Carnosine provides antioxidant protection to stomach lining
Stimulates prostaglandin E2 production for mucosal protection
Enhances gastric mucus production and quality
Promotes gastric epithelial cell regeneration
Inhibits inflammatory cytokines (TNF-α, IL-1β) in gastric tissue

Key findings

what the evidence supports

Highly effective for gastric ulcer healing and mucosal protection
Superior to regular zinc supplements for gastric applications
Generally safe with excellent tolerability profile
Requires empty stomach dosing for optimal effectiveness

Sources: NIH Examine.com · data reviewed 2026-08-02

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Zinc Carnosine?

Documented effects: Gastric mucosal protection; Accelerated ulcer healing; Anti-inflammatory gastric effects; Enhanced gastric antioxidant activity. Protects and strengthens stomach lining against acid damage

How much Zinc Carnosine should you take per day?

The common daily range is 75-150mg twice daily. By goal — gastric protection: 37.5-75mg daily; therapeutic: 75-150mg twice daily; ulcer healing: 75-150mg twice daily for 8-12 weeks; maximum: Do not exceed 300mg daily.

When is the best time to take Zinc Carnosine?

Empty stomach. First effects are typically reported within 1-2 weeks for gastric comfort improvement.

What are the side effects of Zinc Carnosine?

At excessive doses: Generally safe but monitor for:, Copper deficiency with long-term high-dose use, Nausea and digestive upset, Reduced absorption of other minerals, Immune system suppression with excessive zinc. Safety rating at normal doses is 8 out of 10.

What should you not take with Zinc Carnosine?

Separate it from Iron Supplements, Calcium Supplements by two to four hours. May reduce iron absorption

Does Zinc Carnosine interact with medications?

Documented interactions with antibiotics-quinolones, tetracyclines, proton-pump-inhibitors. Discuss these with a pharmacist before combining.

How much Zinc Carnosine is too much?

The tolerable upper intake level is 40 mg per day for adults, per NIH ODS. Above that, the risk of adverse effects rises: Generally safe but monitor for:, Copper deficiency with long-term high-dose use, Nausea and digestive upset.

How do you know if you need Zinc Carnosine?

The marker is Zinc levels, copper levels, gastric function markers, optimal range Adequate zinc and copper balance. Common deficiency signs: Not applicable (therapeutic supplement, not essential nutrient):, Conditions addressed by zinc-carnosine:, Gastric ulcers and mucosal damage, Chronic gastritis and stomach inflammation.

Taken for

74 Digestion

Lactase · Lactobacillus acidophilus · Protease