Rich source of B vitamins and protein
Provides complete protein and essential B vitamins including B12
Saccharomyces cerevisiae
Versatile beneficial yeast that supports digestive health, immune function, and provides essential nutrients including B vitamins, proteins, and minerals
Scientific nameSaccharomyces cerevisiae
FormulaLive yeast organism
Molecular weightN/A - Living yeast organism g/mol
CASN/A - Yeast strain
85
absorption score
8
safety / 10
20
USD per month
6
documented interactions
Check it against something
Saccharomyces cerevisiae with:
- Amylase
- Ashwagandha
- Avocado Oil
- BCAA (Branched-Chain Amino Acids)
- Beetroot Powder
- Beta-Alanine
- Bifidobacterium lactis
- Bifidobacterium longum
- Bovine Collagen
- Caffeine
- Calcium
- Calcium Bone Formula
- Calcium Carbonate
- Casein Protein
- Chicken Collagen
- Choline (Bitartrate)
- Chondroitin Sulfate
- Coconut Oil
- Collagen Peptides
- Comprehensive Immune Support Complex
- Comprehensive Multivitamin-Mineral Complex
- Creatine HCL
- Creatine Monohydrate
- D-Mannose
- DHA
- Electrolyte Blend
- EPA
- Fish Oil (EPA/DHA)
- Folate (5-MTHF)
- Ginger
- Iron Fumarate
- Iron Sulfate
- Joint Mobility Formula
- Keratin
- Krill Oil
- L-Carnitine
- L-Citrulline
- Lactase
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lipase
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Oxide
- Marine Collagen
- Melatonin
- Modafinil
- Olive Oil Extract
- Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
- Papain
- Protease
- Saccharomyces boulardii
- Turmeric
- Vitamin B12 (Cyanocobalamin)
- Vitamin B12 (Methylcobalamin)
- Vitamin C (Ascorbic Acid)
- Vitamin C (Sodium Ascorbate)
- Vitamin D3
- Whey Protein
- Zinc Gluconate
Nothing found
78
out of 100
Works better together
Compatible. Timing differs, so follow each supplement's own window.
What it does
mechanism and evidence for each claimEnhanced immune system function
Strengthens immune response and reduces infection susceptibility
Improved energy and metabolism
Supports energy production and metabolic function
Digestive health and gut support
May support digestive function and gut microbiome health
Antioxidant and cellular protection
Provides antioxidants and supports cellular health
Others take these for the same thing
Same goal, different mechanism — check any of them against this one
Probiotics for Autoimmune Disease Support
Gut health & immune modulation
10-100 billion CFU daily
B
60%
Magnesium Glycinate
Superior absorption sleep & muscle support
200-600 mg
A
90%
Magnesium Citrate
Balanced absorption & digestive support
300-600 mg
A
35%
Chloride
Electrolyte & digestive support
2300mg
A
95%
Bone Broth Collagen
Gut healing & collagen support
20-40g powder
B
85%
Psyllium Husk
Digestive health & cholesterol support
5-15g
A
95%
Every pair we checked
12 combinations scored by the engine
Saccharomyces cerevisiae + Caffeine
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Creatine Monohydrate
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Calcium Carbonate
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Whey Protein
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Lactase
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Bovine Collagen
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + DHA
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Turmeric
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Fish Oil (EPA/DHA)
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Magnesium Oxide
No documented interaction either way
No known interaction
70
Saccharomyces cerevisiae + Vitamin D3
Enhanced immune function and antioxidant protection
Works better together
78
Saccharomyces cerevisiae + Digestive Enzymes
Improved protein digestion and nutrient absorption
Works better together
78
Dosage
Daily1-2 tablespoons
Nutritional support1-2 tablespoons daily with meals
B vitamin supplementation1-2 tablespoons daily
Immune support1-2 tablespoons daily
Protein supplementation2-3 tablespoons daily with meals
When to expect it
First Effects1-2 weeks for nutritional and energy benefits
Peak Benefits4-8 weeks for maximum immune and metabolic benefits
Deficiency DevelopmentNutritional deficiencies develop from poor diet, stress, illness
Toxicity OnsetGenerally safe - rare adverse effects in healthy individuals
How to measure it
MarkerB vitamin levels, protein status, immune markers, uric acid
OptimalAdequate B vitamin levels, normal protein markers
Deficient belowLow B vitamin levels, protein deficiency markers
FrequencyMonitor for nutritional deficiencies and immune health
What actually reaches you
The label counts the carrier, your body does not
Absorption
Very high 85 of 100 · best absorbed form of this compound
Delivered daily
1.3 mg
Cost per 10 mg delivered
$5.23 comparative — uses the absorption score, not a measured percentage
Works better with
+
Vitamin C
Enhanced immune function and antioxidant protection
Both support immune system and provide antioxidant benefits · level B
+
Plant Based Proteins
Complementary amino acid profile for complete protein
Provides amino acids that complement plant proteins · level A
+
Digestive Enzymes
Improved protein digestion and nutrient absorption
Enzymes enhance breakdown and absorption of yeast nutrients · level BWhat not to take with Saccharomyces cerevisiae
!
Antifungal Medications
Antifungals may reduce yeast viability and effectiveness
Antifungal action affects yeast cell function · moderate significance
!
Excessive Heat Processing
High temperatures may reduce nutritional value
Heat damages proteins and heat-sensitive vitamins · moderate significance
!
Alcohol Excess
Excessive alcohol may interfere with B vitamin metabolism
Alcohol affects B vitamin absorption and utilization · moderate significanceMedication interactions
Discuss these with a pharmacist before combiningAntifungals may reduce yeast effectiveness
What to do: Monitor effectiveness during antifungal treatment
Tyramine content may interact with MAO inhibitors
What to do: Use caution with MAO inhibitors
Available forms
Saccharomyces cerevisiae (Nutritional yeast flakes): Complete protein, B vitamin rich, Immune support, Affordable
Food sources
Nutritional yeast flakes
45-60% protein, rich in B vitamins · 85
Brewer's yeast supplements
45-50% protein, B vitamin rich · 80
Fermented foods (bread, beer)
Variable, typically lower concentrations · 70
Fortified foods with yeast extract
Variable B vitamin and protein content · 75
Too little
- Nutritional deficiency symptoms:
- B vitamin deficiencies including fatigue and neurological symptoms
- Protein deficiency and muscle weakness
- Compromised immune function and frequent infections
- Poor energy metabolism and chronic fatigue
- Reduced antioxidant protection and cellular damage
- Suboptimal nutritional status and wellness
Too much
- Generally safe with minimal adverse effects:
- Allergic reactions in yeast-sensitive individuals
- Gout flare-ups in susceptible individuals due to purine content
- Temporary digestive adjustment during initial use
- Safe for daily long-term consumption in most individuals
Who benefits most
vegetarians-vegans
Provides complete protein and vitamin B12 often lacking in plant-based diets
1-2 tablespoons daily
b-vitamin-deficiency
Rich source of B vitamins including B12, folate, and thiamine
1-2 tablespoons daily with meals
immune-system-support
Beta-glucans and nutrients support immune function
1-2 tablespoons daily
energy-metabolism-support
B vitamins support cellular energy production and metabolism
1-2 tablespoons daily with meals
nutritional-enhancement
Provides high-quality protein, vitamins, and minerals
1-2 tablespoons dailyWhere to buy it
Look for Saccharomyces cerevisiae at 1-2 tablespoons per serving. The form that matters here is Saccharomyces cerevisiae (Nutritional yeast flakes).
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What else affects it
Beyond other supplements
!
Excessive heat processing
High temperatures may reduce nutritional value
Heat damages proteins and heat-sensitive vitamins
!
Alcohol excess
Excessive alcohol may interfere with B vitamin metabolism
Alcohol affects B vitamin absorption and utilizationHow it works
- Provides complete protein with all essential amino acids
- Contains beta-glucans that stimulate immune system activity
- Supplies B vitamins essential for energy metabolism and enzyme function
- Provides antioxidants including glutathione and selenium
- Contains minerals including chromium, selenium, and potassium
- Supports gut health through beneficial compounds and fiber
Key findings
what the evidence supports- Proven nutritional benefits including complete protein and B vitamins
- Strong evidence for immune system support through beta-glucans
- Good safety profile with minimal adverse effects in healthy individuals
- Valuable nutritional supplement especially for vegetarians and vegans
Sources: NIH Examine.com · data reviewed 2026-08-01
Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →
Common questions
What are the benefits of Saccharomyces cerevisiae?
Documented effects: Rich source of B vitamins and protein; Enhanced immune system function; Improved energy and metabolism; Digestive health and gut support. Provides complete protein and essential B vitamins including B12
How much Saccharomyces cerevisiae should you take per day?
The common daily range is 1-2 tablespoons. By goal — nutritional support: 1-2 tablespoons daily with meals; b vitamin supplementation: 1-2 tablespoons daily; immune support: 1-2 tablespoons daily; protein supplementation: 2-3 tablespoons daily with meals.
When is the best time to take Saccharomyces cerevisiae?
With meals daily. First effects are typically reported within 1-2 weeks for nutritional and energy benefits.
What are the side effects of Saccharomyces cerevisiae?
At excessive doses: Generally safe with minimal adverse effects:, Allergic reactions in yeast-sensitive individuals, Gout flare-ups in susceptible individuals due to purine content, Temporary digestive adjustment during initial use, Safe for daily long-term consumption in most individuals. Safety rating at normal doses is 8 out of 10.
What should you not take with Saccharomyces cerevisiae?
Separate it from Antifungal Medications, Excessive Heat Processing, Alcohol Excess by two to four hours. Antifungals may reduce yeast viability and effectiveness
Does Saccharomyces cerevisiae interact with medications?
Documented interactions with antifungal-medications, monoamine-oxidase-inhibitors. Discuss these with a pharmacist before combining.
How do you know if you need Saccharomyces cerevisiae?
The marker is B vitamin levels, protein status, immune markers, uric acid, optimal range Adequate B vitamin levels, normal protein markers. Common deficiency signs: Nutritional deficiency symptoms:, B vitamin deficiencies including fatigue and neurological symptoms, Protein deficiency and muscle weakness, Compromised immune function and frequent infections.