Superior cardiovascular health support
Provides exceptional heart health benefits and cardiovascular protection
Macadamia Oil
Premium macadamia nut oil exceptionally rich in omega-9 fatty acids and rare palmitoleic acid, supporting cardiovascular health and metabolic function
Scientific nameMacadamia integrifolia oil
FormulaRich in oleic acid, palmitoleic acid, and palmitic acid
Molecular weightVariable triglyceride mixture g/mol
CAS129811-19-4
95
absorption score
8
safety / 10
60
USD per month
5
documented interactions
Check it against something
Macadamia Oil with:
- Amylase
- Ashwagandha
- Avocado Oil
- BCAA (Branched-Chain Amino Acids)
- Beetroot Powder
- Beta-Alanine
- Bifidobacterium lactis
- Bifidobacterium longum
- Bovine Collagen
- Caffeine
- Calcium
- Calcium Bone Formula
- Calcium Carbonate
- Casein Protein
- Chicken Collagen
- Choline (Bitartrate)
- Chondroitin Sulfate
- Coconut Oil
- Collagen Peptides
- Comprehensive Immune Support Complex
- Comprehensive Multivitamin-Mineral Complex
- Creatine HCL
- Creatine Monohydrate
- D-Mannose
- DHA
- Electrolyte Blend
- EPA
- Fish Oil (EPA/DHA)
- Folate (5-MTHF)
- Ginger
- Iron Fumarate
- Iron Sulfate
- Joint Mobility Formula
- Keratin
- Krill Oil
- L-Carnitine
- L-Citrulline
- Lactase
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lipase
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Oxide
- Marine Collagen
- Melatonin
- Modafinil
- Olive Oil Extract
- Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
- Papain
- Protease
- Saccharomyces boulardii
- Turmeric
- Vitamin B12 (Cyanocobalamin)
- Vitamin B12 (Methylcobalamin)
- Vitamin C (Ascorbic Acid)
- Vitamin C (Sodium Ascorbate)
- Vitamin D3
- Whey Protein
- Zinc Gluconate
Nothing found
70
out of 100
No known interaction
No documented interaction. Standard timing for each applies.
What it does
mechanism and evidence for each claimMetabolic health and insulin sensitivity
Enhances metabolic function and insulin sensitivity
Anti-inflammatory and antioxidant effects
Provides potent anti-inflammatory and cellular protection
Skin health and beauty enhancement
Supports skin health, elasticity, and anti-aging benefits
High-temperature cooking stability
Excellent stability for cooking without oxidation or degradation
Others take these for the same thing
Same goal, different mechanism — check any of them against this one
Ashwagandha
Stress management & energy
300-600mg
A
75%
Vitamin B12 (Cyanocobalamin)
Energy & nerve support
250-1000 mcg
A
70%
Coenzyme Q10 (CoQ10)
Heart health & cellular energy
100-200mg
A
10%
Fish Oil (EPA/DHA)
Heart & brain health
1-2g EPA/DHA
A
85%
Phosphorus
Bone health & energy metabolism
700-1250mg
A
80%
Vitamin B3 (Niacinamide)
Energy & skin health (no flush)
100-1000 mg
A
88%
Every pair we checked
12 combinations scored by the engine
Macadamia Oil + Caffeine
No documented interaction either way
No known interaction
70
Macadamia Oil + Creatine Monohydrate
No documented interaction either way
No known interaction
70
Macadamia Oil + Vitamin D3
No documented interaction either way
No known interaction
70
Macadamia Oil + Calcium Carbonate
No documented interaction either way
No known interaction
70
Macadamia Oil + Whey Protein
No documented interaction either way
No known interaction
70
Macadamia Oil + Lactase
No documented interaction either way
No known interaction
70
Macadamia Oil + Bovine Collagen
No documented interaction either way
No known interaction
70
Macadamia Oil + DHA
No documented interaction either way
No known interaction
70
Macadamia Oil + Turmeric
No documented interaction either way
No known interaction
70
Macadamia Oil + Fish Oil (EPA/DHA)
No documented interaction either way
No known interaction
70
Macadamia Oil + Magnesium Oxide
No documented interaction either way
No known interaction
70
Macadamia Oil + Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
Optimal fatty acid balance and comprehensive health benefits
Works better together
78
Dosage
Daily15-30ml
Cardiovascular support15-30ml daily
Metabolic health15-30ml daily
Skin beauty15ml daily + topical
Cooking useAs needed for culinary applications
When to expect it
First Effects2-4 weeks for initial metabolic and cardiovascular benefits
Peak Benefits8-16 weeks for sustained health and beauty benefits
Deficiency DevelopmentNot applicable - macadamia oil is not essential
Toxicity OnsetVery rare, mainly allergic reactions or caloric excess
How to measure it
MarkerLipid panel, glucose metabolism markers, inflammatory markers
OptimalImproved cholesterol ratios, enhanced insulin sensitivity, reduced inflammation
Deficient belowPoor lipid profile, insulin resistance markers
FrequencyEvery 6-12 months for metabolic health assessment
What actually reaches you
The label counts the carrier, your body does not
Absorption
Very high 95 of 100 · best absorbed form of this compound
Delivered daily
21.4 mg
Cost per 100 mg delivered
$9.36 comparative — uses the absorption score, not a measured percentage
Works better with
+
Omega 3 Fatty Acids
Optimal fatty acid balance and comprehensive health benefits
Balanced omega profile provides synergistic cardiovascular and metabolic support · level B
+
Antioxidant Rich Foods
Enhanced antioxidant protection and oil stability
Dietary antioxidants work with oil's natural antioxidants for cellular protection · level B
+
Fat Soluble Vitamins
Enhanced absorption of vitamins A, D, E, K
Healthy fats facilitate absorption of fat-soluble nutrients · level AWhat not to take with Macadamia Oil
!
Excessive Omega 6 Oils
High omega-6 intake may reduce macadamia oil's anti-inflammatory benefits
Imbalanced fatty acid ratios promote inflammatory pathways · moderate significance
!
Heat Light Exposure
Excessive heat and light reduce oil quality over time
Oxidation gradually degrades beneficial compounds · mild significanceMedication interactions
Discuss these with a pharmacist before combiningMay enhance insulin sensitivity effects
What to do: Monitor blood glucose if diabetic
May enhance cholesterol-lowering effects
What to do: Beneficial combination
Available forms
Cold-Pressed Macadamia Oil (Extra Virgin): Unique fatty acids, Metabolic benefits, Cooking stability, Skin health
Food sources
Cold-pressed macadamia oil
Pure oil (15-30ml daily) · 95
Raw macadamia nuts
Natural oil content in nuts · 85
Macadamia nut butter
Concentrated nut oil · 80
Macadamia oil supplements
Encapsulated oil · 90
Too little
- No specific macadamia oil deficiency as it's not essential:
- Missing unique palmitoleic acid metabolic benefits
- Suboptimal omega-9 fatty acid status
- Reduced skin health and barrier function
- Missing premium cardiovascular protection
- Lower antioxidant protection from cooking oils
Too much
- Extremely safe with minimal side effects:
- Weight gain with excessive caloric intake
- Allergic reactions in tree nut sensitive individuals
- Digestive upset with very large amounts
- Generally well tolerated by most people
Who benefits most
cardiovascular-health-optimization
Premium heart health support with unique fatty acid profile
1-2 tablespoons daily (15-30ml)
metabolic-health-support
Enhanced insulin sensitivity and glucose metabolism
1-2 tablespoons daily
skin-health-beauty
Internal and topical skin health and anti-aging support
1 tablespoon daily + topical use
gourmet-cooking-health
Premium cooking oil for health-conscious culinary applications
As needed for cooking
anti-inflammatory-support
Natural anti-inflammatory and antioxidant protection
1-2 tablespoons dailyWhere to buy it
Look for Macadamia Oil at 15-30ml per serving. The form that matters here is Cold-Pressed Macadamia Oil (Extra Virgin).
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What else affects it
Beyond other supplements
+
Antioxidant rich foods
Enhanced antioxidant protection and oil stability
Dietary antioxidants work with oil's natural antioxidants for cellular protection
!
Excessive omega 6 oils
High omega-6 intake may reduce macadamia oil's anti-inflammatory benefits
Imbalanced fatty acid ratios promote inflammatory pathwaysHow it works
- High oleic acid content (60-80%) supports optimal cholesterol ratios
- Palmitoleic acid (16-25%) enhances insulin sensitivity and glucose metabolism
- Monounsaturated fats reduce inflammation and support cardiovascular health
- Omega-7 fatty acids support skin barrier function and cellular regeneration
- Natural antioxidants protect against oxidative stress and cellular damage
- Stable fatty acid profile resists oxidation during cooking and storage
Key findings
what the evidence supports- Good evidence for cardiovascular health benefits
- Emerging research on palmitoleic acid and metabolic health
- Strong stability profile for cooking applications
- Excellent safety with consideration for tree nut allergies
Sources: NIH Examine.com · data reviewed 2026-08-01
Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →
Common questions
What are the benefits of Macadamia Oil?
Documented effects: Superior cardiovascular health support; Metabolic health and insulin sensitivity; Anti-inflammatory and antioxidant effects; Skin health and beauty enhancement. Provides exceptional heart health benefits and cardiovascular protection
How much Macadamia Oil should you take per day?
The common daily range is 15-30ml. By goal — cardiovascular support: 15-30ml daily; metabolic health: 15-30ml daily; skin beauty: 15ml daily + topical; cooking use: As needed for culinary applications.
When is the best time to take Macadamia Oil?
With meals. First effects are typically reported within 2-4 weeks for initial metabolic and cardiovascular benefits.
What are the side effects of Macadamia Oil?
At excessive doses: Extremely safe with minimal side effects:, Weight gain with excessive caloric intake, Allergic reactions in tree nut sensitive individuals, Digestive upset with very large amounts, Generally well tolerated by most people. Safety rating at normal doses is 8 out of 10.
What should you not take with Macadamia Oil?
Separate it from Excessive Omega 6 Oils, Heat Light Exposure by two to four hours. High omega-6 intake may reduce macadamia oil's anti-inflammatory benefits
Does Macadamia Oil interact with medications?
Documented interactions with diabetes-medications, cholesterol-medications. Discuss these with a pharmacist before combining.
How do you know if you need Macadamia Oil?
The marker is Lipid panel, glucose metabolism markers, inflammatory markers, optimal range Improved cholesterol ratios, enhanced insulin sensitivity, reduced inflammation. Common deficiency signs: No specific macadamia oil deficiency as it's not essential:, Missing unique palmitoleic acid metabolic benefits, Suboptimal omega-9 fatty acid status, Reduced skin health and barrier function.