Krill Oil

Premium marine oil from Antarctic krill containing phospholipid-bound omega-3 fatty acids and astaxanthin for superior absorption and antioxidant protection

Scientific nameEuphausia superba oil FormulaPhospholipid-bound EPA and DHA Molecular weightVariable - phospholipid complex g/mol

95 absorption score

8 safety / 10

60 USD per month

6 documented interactions

Check it against something

Evidence level B

Krill Oil with:

78 out of 100

Works better together Compatible. Timing differs, so follow each supplement's own window.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Superior omega-3 absorption and bioavailability

Phospholipid-bound omega-3s are better absorbed than traditional fish oil

Phospholipid structure allows easier cellular uptake and membrane incorporation Evidence B-grade 2-6 weeks for improved omega-3 status

Cardiovascular health and heart protection

Supports healthy cholesterol levels, blood pressure, and cardiovascular function

EPA/DHA reduce inflammation and support endothelial function Evidence B-grade 6-12 weeks for cardiovascular benefits

Antioxidant protection with astaxanthin

Natural astaxanthin provides powerful antioxidant protection

Astaxanthin protects omega-3s from oxidation and provides cellular protection Evidence B-grade 4-8 weeks for antioxidant benefits

Anti-inflammatory effects

Reduces systemic inflammation and inflammatory markers

EPA produces anti-inflammatory mediators and reduces pro-inflammatory cytokines Evidence B-grade 4-8 weeks for anti-inflammatory effects

Brain health and cognitive support

Supports memory, cognitive function, and neurological health

Phospholipid-bound DHA better incorporates into brain tissue Evidence C-grade 8-16 weeks for cognitive benefits

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Probiotics for Autoimmune Disease Support Gut health & immune modulation 10-100 billion CFU daily B 60% Magnesium Glycinate Superior absorption sleep & muscle support 200-600 mg A 90% Coenzyme Q10 (CoQ10) Heart health & cellular energy 100-200mg A 10% Magnesium Citrate Balanced absorption & digestive support 300-600 mg A 35% Fish Oil (EPA/DHA) Heart & brain health 1-2g EPA/DHA A 85% Chloride Electrolyte & digestive support 2300mg A 95%

Or a different form of the same thing

the comparison people search most

Krill Oil vs Fish Oil (EPA/DHA) absorption 95 against 85 · $60 against $25 a month 85%

All Omega forms ranked by absorption →

Every pair we checked

12 combinations scored by the engine

Krill Oil + CLA (Conjugated Linoleic Acid) High omega-6 intake reduces krill oil effectiveness Needs attention 58

Krill Oil + Caffeine No documented interaction either way No known interaction 70

Krill Oil + Creatine Monohydrate No documented interaction either way No known interaction 70

Krill Oil + Calcium Carbonate No documented interaction either way No known interaction 70

Krill Oil + Whey Protein No documented interaction either way No known interaction 70

Krill Oil + Lactase No documented interaction either way No known interaction 70

Krill Oil + Bovine Collagen No documented interaction either way No known interaction 70

Krill Oil + DHA No documented interaction either way No known interaction 70

Krill Oil + Turmeric No documented interaction either way No known interaction 70

Krill Oil + Phosphatidylserine Enhanced cognitive and brain health benefits Works better together 75

Krill Oil + Vitamin D3 Enhanced antioxidant protection and stability Works better together 78

Krill Oil + Coenzyme Q10 (CoQ10) Synergistic cardiovascular and antioxidant benefits Works better together 78

Dosage

With meals for absorption

Daily500-1,500 mg

General health500-1,000 mg krill oil daily

Cardiovascular support1,000-2,000 mg krill oil daily

Anti inflammatory1,500-2,500 mg krill oil daily

Cognitive support1,000-1,500 mg krill oil daily

Before you take it

VeganNo — animal derived

When to expect it

First Effects2-4 weeks for improved omega-3 status and reduced inflammation

Peak Benefits8-12 weeks for maximum cardiovascular and cognitive benefits

Deficiency DevelopmentModern diets low in marine omega-3s create widespread deficiency

Toxicity OnsetGenerally safe - monitor for bleeding with very high doses

How to measure it

$150-300

MarkerOmega-3 index, EPA/DHA levels, inflammatory markers (CRP)

OptimalOmega-3 index >8%, balanced EPA/DHA levels, low inflammation

Deficient belowOmega-3 index <4%, low EPA/DHA levels, elevated inflammation

FrequencyMonitor every 3-6 months during supplementation

What people actually reported to the FDA

CAERS, 557 reports naming it as the suspect

Most reported effects

Dyspnoea 68

Diarrhoea 52

Nausea 48

Dizziness 41

Hypersensitivity 36

Excluded from the list above: choking (38). Those are people struggling with the tablet itself, not with the compound.

Named as the suspect 557 reports of 1,000+ that mention it at all

Serious outcome 83% hospitalisation, emergency room or worse

Other Serious or Important Medical Event360

Hospitalization174

Visited a Health Care Provider117

Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →

What actually reaches you

The label counts the carrier, your body does not

Absorption Very high 95 of 100 · best absorbed form of this compound

Delivered daily 950 mg

Cost per 100 mg delivered $0.21 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented

Vitamin E

Enhanced antioxidant protection and stability

Vitamin E works with astaxanthin to protect omega-3s · level B

Coq10

Synergistic cardiovascular and antioxidant benefits

Complementary cardioprotective and cellular energy effects · level B

Phosphatidylserine

Enhanced cognitive and brain health benefits

Both support neuronal membrane function and brain health · level C

What not to take with Krill Oil

3 documented

Omega 6 Excess

High omega-6 intake reduces krill oil effectiveness

Competes for same enzymes and promotes inflammation · high significance

Trans Fats

Trans fats interfere with omega-3 metabolism

Disrupts fatty acid metabolism and membrane function · high significance

Oxidized Oils

Damaged oils counteract antioxidant and anti-inflammatory effects

Oxidized oils promote inflammation and oxidative stress · moderate significance

Medication interactions

Discuss these with a pharmacist before combining

anticoagulants Moderate

May enhance blood-thinning effects

What to do: Monitor INR and bleeding time carefully

blood-pressure-medications Minor

May enhance blood pressure lowering effects

What to do: Monitor blood pressure regularly

Available forms

bioavailability compared

Best absorbed form of Omega — 95% against 4 alternatives. Compare all forms →

Antarctic krill oil (phospholipid complex) 95

Antarctic krill oil (phospholipid complex): Superior absorption, No fishy burps, Antioxidant protection, Sustainable source

Food sources

before you supplement

Antarctic krill (Euphausia superba) Natural source but not practical for consumption · 100

Krill oil supplements 50-150 mg EPA/DHA per 500mg capsule · 95

Phospholipid omega-3 complexes Variable EPA/DHA content · 90

Marine phospholipid supplements Combined with other marine lipids · 85

Too little

deficiency signs

Omega-3 deficiency symptoms (same as fish oil but may develop faster):
Cardiovascular disease risk and poor heart health
Cognitive decline and memory problems
Chronic inflammation and joint pain
Mood disorders and depression
Poor skin health and wound healing
Compromised immune function

Too much

toxicity signs

Generally safe with potential for mild adverse effects:
Allergic reactions in shellfish-sensitive individuals
Increased bleeding risk with very high doses
Digestive discomfort in sensitive individuals
Safe for long-term use at appropriate doses

Who benefits most

superior-absorption-seekers

Better absorbed omega-3s for those with absorption issues

500-1,000 mg krill oil daily

cardiovascular-health-seekers

Supports heart health with superior bioavailability

1,000-2,000 mg krill oil daily

antioxidant-protection-seekers

Natural astaxanthin provides additional antioxidant benefits

500-1,500 mg krill oil daily

digestive-sensitive-individuals

Less likely to cause fishy burps or digestive upset

500-1,000 mg krill oil daily

cognitive-health-seekers

Better brain uptake of phospholipid-bound omega-3s

1,000-1,500 mg krill oil daily

Where to buy it

compare forms first

Look for Krill Oil at 500-1,500 mg per serving. The form that matters here is Antarctic krill oil (phospholipid complex).

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What else affects it

Beyond other supplements

Trans fats

Trans fats interfere with omega-3 metabolism

Disrupts fatty acid metabolism and membrane function

Oxidized oils

Damaged oils counteract antioxidant and anti-inflammatory effects

Oxidized oils promote inflammation and oxidative stress

How it works

Phospholipid structure allows superior cellular uptake and membrane incorporation
EPA/DHA more efficiently delivered to target tissues
Natural astaxanthin protects omega-3s from oxidation
Better crossing of blood-brain barrier due to phospholipid structure
Reduces inflammatory markers more effectively than fish oil
Supports cellular membrane health and function

Key findings

what the evidence supports

Superior bioavailability compared to fish oil
Effective for cardiovascular health and lipid management
Good safety profile with minimal adverse effects
Natural astaxanthin provides additional antioxidant benefits

Sources: NIH Examine.com · data reviewed 2026-08-02

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Krill Oil?

Documented effects: Superior omega-3 absorption and bioavailability; Cardiovascular health and heart protection; Antioxidant protection with astaxanthin; Anti-inflammatory effects. Phospholipid-bound omega-3s are better absorbed than traditional fish oil

How much Krill Oil should you take per day?

The common daily range is 500-1,500 mg. By goal — general health: 500-1,000 mg krill oil daily; cardiovascular support: 1,000-2,000 mg krill oil daily; anti inflammatory: 1,500-2,500 mg krill oil daily; cognitive support: 1,000-1,500 mg krill oil daily.

When is the best time to take Krill Oil?

With meals for absorption. First effects are typically reported within 2-4 weeks for improved omega-3 status and reduced inflammation.

What are the side effects of Krill Oil?

At excessive doses: Generally safe with potential for mild adverse effects:, Allergic reactions in shellfish-sensitive individuals, Increased bleeding risk with very high doses, Digestive discomfort in sensitive individuals, Safe for long-term use at appropriate doses. Safety rating at normal doses is 8 out of 10.

What should you not take with Krill Oil?

Separate it from Omega 6 Excess, Trans Fats, Oxidized Oils by two to four hours. High omega-6 intake reduces krill oil effectiveness

Does Krill Oil interact with medications?

Documented interactions with anticoagulants, blood-pressure-medications. Discuss these with a pharmacist before combining.

How do you know if you need Krill Oil?

The marker is Omega-3 index, EPA/DHA levels, inflammatory markers (CRP), optimal range Omega-3 index >8%, balanced EPA/DHA levels, low inflammation. Common deficiency signs: Omega-3 deficiency symptoms (same as fish oil but may develop faster):, Cardiovascular disease risk and poor heart health, Cognitive decline and memory problems, Chronic inflammation and joint pain.

Taken for

52 Heart

Fish Oil (EPA/DHA) · EPA · Olive Oil Extract

74 Digestion

Lactase · Lactobacillus acidophilus · Protease