Jujube

Traditional Chinese date fruit supporting natural sleep enhancement, anxiety relief, and digestive comfort through gentle calming properties

Scientific nameZiziphus jujuba FormulaVarious saponins and flavonoids Molecular weightVariable natural compounds g/mol CASVarious natural compounds

70 absorption score

9 safety / 10

20 USD per month

5 documented interactions

Check it against something

Evidence level C

Jujube with:

75 out of 100

Works better together Compatible. Timing differs, so follow each supplement's own window.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Sleep quality and natural sedation

Promotes natural sleep and improves sleep quality

Saponins and flavonoids provide mild sedative effects supporting sleep Evidence C-grade 30-60 minutes before sleep, 2-4 weeks sustained

Anxiety relief and calming support

Gentle anxiety reduction and nervous system calming

Natural compounds modulate neurotransmitter activity for relaxation Evidence C-grade 1-3 hours acute, 2-6 weeks sustained

Digestive health and comfort

Supports digestive health and soothes digestive discomfort

Traditional digestive tonic effects and gentle fiber content Evidence C-grade 30 minutes to 2 hours post-consumption

Antioxidant protection and immune support

Provides antioxidant benefits and immune system support

Flavonoids and vitamin C provide antioxidant and immune-enhancing effects Evidence C-grade 4-12 weeks

Blood sugar and metabolic support

Supports healthy blood sugar levels and metabolism

Fiber and natural compounds help regulate glucose absorption and metabolism Evidence C-grade 4-12 weeks

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Melatonin Sleep support & circadian rhythm 0.5-3mg A 50% Ashwagandha Stress management & energy 300-600mg A 75% Magnesium Glycinate Superior absorption sleep & muscle support 200-600 mg A 90% L-Theanine Calm focus & stress relief 100-400mg B 90% Glycine Sleep quality & collagen support 3-10g A 95% GABA (Gamma-Aminobutyric Acid) Natural relaxation & anxiety relief 250-1000mg C 30%

Every pair we checked

12 combinations scored by the engine

Jujube + Caffeine May oppose sleep-promoting effects Needs attention 58

Jujube + Creatine Monohydrate No documented interaction either way No known interaction 70

Jujube + Calcium Carbonate No documented interaction either way No known interaction 70

Jujube + Whey Protein No documented interaction either way No known interaction 70

Jujube + Lactase No documented interaction either way No known interaction 70

Jujube + Bovine Collagen No documented interaction either way No known interaction 70

Jujube + DHA No documented interaction either way No known interaction 70

Jujube + Turmeric No documented interaction either way No known interaction 70

Jujube + Fish Oil (EPA/DHA) No documented interaction either way No known interaction 70

Jujube + Chamomile Enhanced sleep support and gentle calming Works better together 75

Jujube + Ginger Comprehensive digestive support and comfort Works better together 75

Jujube + Vitamin D3 Enhanced antioxidant protection and immune support Works better together 75

Dosage

Evening before sleep

Daily500-2000mg

Sleep support500-2000mg daily

Anxiety calming500-1500mg daily

Digestive support500-1000mg with meals

Antioxidant support500-1000mg daily

Before you take it

VeganYes

When to expect it

First Effects30-60 minutes for acute calming and digestive benefits

Peak Benefits2-8 weeks for sustained sleep support and stress reduction

Deficiency DevelopmentNot applicable - herbal supplement

Toxicity OnsetVery rare, excellent safety profile

How to measure it

$50-100

MarkerBlood glucose, inflammatory markers if relevant

OptimalStable blood sugar, reduced inflammation markers

Deficient belowNot applicable for herbal supplement

FrequencyEvery 6-12 months for general wellness monitoring

What people actually reported to the FDA

CAERS, 1 reports naming it as the suspect

Most reported effects

Diabetes mellitus 1

Gallbladder disorder 1

Hypotension 1

Myocardial infarction 1

Renal disorder 1

Named as the suspect 1 reports of 1 that mention it at all

Serious outcome 100% hospitalisation, emergency room or worse

Hospitalization1

Other Serious or Important Medical Event1

Other Serious Outcome1

Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →

What actually reaches you

The label counts the carrier, your body does not

Absorption High 70 of 100 · absorbs well relative to other forms

Delivered daily 875 mg

Cost per 100 mg delivered $0.08 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented

Chamomile

Enhanced sleep support and gentle calming

Synergistic mild sedative effects for natural sleep enhancement · level C

Ginger

Comprehensive digestive support and comfort

Both support digestive health through complementary mechanisms · level C

Vitamin C

Enhanced antioxidant protection and immune support

Additive antioxidant and immune-supporting effects · level C

What not to take with Jujube

2 documented

Stimulants Caffeine

May oppose sleep-promoting effects

Stimulants counteract mild sedative and calming effects · mild significance

High Sugar Foods

May interfere with blood sugar benefits

High sugar intake opposes glucose regulation benefits · mild significance

Medication interactions

Discuss these with a pharmacist before combining

diabetes-medications Minor

May affect blood sugar levels

What to do: Monitor blood glucose levels

sedative-medications Minor

May enhance mild sedative effects

What to do: Monitor for increased sleepiness

no-major-interactions None

Generally safe with most medications

What to do: Safe concurrent use

Available forms

bioavailability compared

Jujube Fruit Extract (Standardized) 70

Jujube Fruit Extract (Standardized): Excellent safety, Traditional use, Gentle effects, Natural sleep support

Food sources

before you supplement

Fresh jujube fruit Natural compounds and vitamin C · 75

Dried jujube dates Concentrated nutrients and compounds · 70

Jujube tea Moderate compound extraction · 65

Standardized extracts Concentrated active compounds · 70

Too little

deficiency signs

Not applicable (herbal supplement, not essential nutrient):
General symptoms addressed by jujube:
Mild sleep difficulties and restlessness
General anxiety and nervous tension
Digestive discomfort and poor gut health
Low immunity and frequent minor illnesses
Blood sugar irregularities and metabolic issues

Too much

toxicity signs

Extremely safe with minimal side effects:
Rare allergic reactions in sensitive individuals
Mild digestive upset with very large amounts
Possible blood sugar effects in diabetics
Generally well tolerated by most people

Who benefits most

sleep-quality-mild-insomnia

Gentle natural sleep support for mild sleep difficulties and insomnia

500-2000mg daily (or 3-10g dried fruit)

anxiety-stress-mild

Gentle anxiety relief and stress reduction for daily stress management

500-1500mg daily

digestive-health-comfort

Digestive support and comfort for general digestive wellness

500-1000mg with meals

immune-antioxidant-support

Antioxidant protection and immune system support

500-1000mg daily

blood-sugar-metabolic-support

Natural blood sugar and metabolic support

500-1000mg daily

Where to buy it

compare forms first

Look for Jujube at 500-2000mg per serving. The form that matters here is Jujube Fruit Extract (Standardized).

Find on Amazon

Affiliate link — we may earn a commission at no cost to you.

What else affects it

Beyond other supplements

High sugar foods

May interfere with blood sugar benefits

High sugar intake opposes glucose regulation benefits

How it works

Saponins and triterpenes provide mild sedative effects supporting natural sleep
Flavonoids modulate neurotransmitter activity promoting relaxation and anxiety relief
Natural fiber and compounds support healthy digestion and gut comfort
Vitamin C and antioxidant compounds provide immune system and cellular protection
Natural sugars and fiber help regulate glucose absorption and metabolism
Traditional 'qi and blood tonifying' effects support overall vitality and calm

Key findings

what the evidence supports

Extensive traditional use for sleep and anxiety support
Limited clinical research but promising preliminary studies
Excellent safety profile with thousands of years of use
Gentle effects suitable for long-term use

Sources: NIH Examine.com · data reviewed 2026-08-02

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Jujube?

Documented effects: Sleep quality and natural sedation; Anxiety relief and calming support; Digestive health and comfort; Antioxidant protection and immune support. Promotes natural sleep and improves sleep quality

How much Jujube should you take per day?

The common daily range is 500-2000mg. By goal — sleep support: 500-2000mg daily; anxiety calming: 500-1500mg daily; digestive support: 500-1000mg with meals; antioxidant support: 500-1000mg daily.

When is the best time to take Jujube?

Evening before sleep. First effects are typically reported within 30-60 minutes for acute calming and digestive benefits.

What are the side effects of Jujube?

At excessive doses: Extremely safe with minimal side effects:, Rare allergic reactions in sensitive individuals, Mild digestive upset with very large amounts, Possible blood sugar effects in diabetics, Generally well tolerated by most people. Safety rating at normal doses is 9 out of 10.

What should you not take with Jujube?

Separate it from Stimulants Caffeine, High Sugar Foods by two to four hours. May oppose sleep-promoting effects

Does Jujube interact with medications?

Documented interactions with diabetes-medications, sedative-medications, no-major-interactions. Discuss these with a pharmacist before combining.

How do you know if you need Jujube?

The marker is Blood glucose, inflammatory markers if relevant, optimal range Stable blood sugar, reduced inflammation markers. Common deficiency signs: Not applicable (herbal supplement, not essential nutrient):, General symptoms addressed by jujube:, Mild sleep difficulties and restlessness, General anxiety and nervous tension.

Taken for

28 Sleep & Stress

Melatonin · Magnesium Glycinate · Ashwagandha