Clinically proven cough relief
Scientifically validated reduction in cough frequency and severity
Ivy Leaf
Traditional respiratory herb with expectorant and bronchodilator properties, clinically proven for cough relief and bronchial health
Scientific nameHedera helix
FormulaVarious saponins and flavonoids
Molecular weightVariable natural compounds g/mol
CASVarious natural compounds
70
absorption score
8
safety / 10
30
USD per month
4
documented interactions
Check it against something
Ivy Leaf with:
- Amylase
- Ashwagandha
- Avocado Oil
- BCAA (Branched-Chain Amino Acids)
- Beetroot Powder
- Beta-Alanine
- Bifidobacterium lactis
- Bifidobacterium longum
- Bovine Collagen
- Caffeine
- Calcium
- Calcium Bone Formula
- Calcium Carbonate
- Casein Protein
- Chicken Collagen
- Choline (Bitartrate)
- Chondroitin Sulfate
- Coconut Oil
- Collagen Peptides
- Comprehensive Immune Support Complex
- Comprehensive Multivitamin-Mineral Complex
- Creatine HCL
- Creatine Monohydrate
- D-Mannose
- DHA
- Electrolyte Blend
- EPA
- Fish Oil (EPA/DHA)
- Folate (5-MTHF)
- Ginger
- Iron Fumarate
- Iron Sulfate
- Joint Mobility Formula
- Keratin
- Krill Oil
- L-Carnitine
- L-Citrulline
- Lactase
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lipase
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Oxide
- Marine Collagen
- Melatonin
- Modafinil
- Olive Oil Extract
- Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
- Papain
- Protease
- Saccharomyces boulardii
- Thyme
- Turmeric
- Vitamin B12 (Cyanocobalamin)
- Vitamin B12 (Methylcobalamin)
- Vitamin C (Ascorbic Acid)
- Vitamin C (Sodium Ascorbate)
- Vitamin D3
- Whey Protein
- Zinc Gluconate
Nothing found
80
out of 100
Works better together
Compatible. Timing differs, so follow each supplement's own window.
What it does
mechanism and evidence for each claimBronchodilator and airway support
Natural bronchodilator effects improving airway function and breathing
Expectorant and mucus clearance
Helps clear respiratory secretions and improve mucus clearance
Anti-inflammatory respiratory support
Reduces inflammation in respiratory tract and airways
Chronic respiratory condition support
Long-term support for chronic respiratory conditions like COPD and asthma
Others take these for the same thing
Same goal, different mechanism — check any of them against this one
Probiotics for Autoimmune Disease Support
Gut health & immune modulation
10-100 billion CFU daily
B
60%
Vitamin D3
Bone health & immune support
1000-2000 IU
A
85%
Zinc Picolinate
Superior immune & healing support
15-30 mg
A
95%
L-Lysine
Immune support & collagen synthesis
1-3g
A
90%
Oregano Oil
Powerful respiratory antimicrobial
100-300mg
B
85%
Oregano Oil for Antimicrobial Protection
Antimicrobial & pathogen defense
1-3 drops diluted daily
B
75%
Every pair we checked
12 combinations scored by the engine
Ivy Leaf + Caffeine
No documented interaction either way
No known interaction
70
Ivy Leaf + Creatine Monohydrate
No documented interaction either way
No known interaction
70
Ivy Leaf + Vitamin D3
No documented interaction either way
No known interaction
70
Ivy Leaf + Calcium Carbonate
No documented interaction either way
No known interaction
70
Ivy Leaf + Whey Protein
No documented interaction either way
No known interaction
70
Ivy Leaf + Lactase
No documented interaction either way
No known interaction
70
Ivy Leaf + Bovine Collagen
No documented interaction either way
No known interaction
70
Ivy Leaf + DHA
No documented interaction either way
No known interaction
70
Ivy Leaf + Turmeric
No documented interaction either way
No known interaction
70
Ivy Leaf + Thyme
Enhanced expectorant and bronchial support
Works better together
80
Ivy Leaf + Mullein
Synergistic respiratory soothing and expectorant support
Works better together
80
Ivy Leaf + Licorice Root
Enhanced anti-inflammatory and expectorant effects
Works better together
80
Dosage
Daily25-50mg
Acute cough25-50mg daily
Chronic respiratory25-50mg daily long-term
Bronchial support25-35mg daily
Expectorant support25-50mg daily
Before you take it
VeganYes
When to expect it
First Effects2-7 days for cough relief and expectorant effects
Peak Benefits1-4 weeks for sustained bronchial support and respiratory health
Deficiency DevelopmentNot applicable - herbal supplement
Toxicity OnsetRare with proper dosing, mainly allergic reactions
How to measure it
MarkerGenerally not needed - assess through symptom improvement
OptimalImproved respiratory function and reduced cough
Deficient belowNot applicable for herbal supplement
FrequencyMonitor through respiratory symptom improvement and lung function
What people actually reported to the FDA
CAERS, 7 reports naming it as the suspectMost reported effects
Excluded from the list above: choking (3). Those are people struggling with the tablet itself, not with the compound.
Named as the suspect
7 reports
of 7 that mention it at all
Serious outcome
77%
hospitalisation, emergency room or worse
Other Serious or Important Medical Event6
Visited a Health Care Provider2
Other Serious Outcome2
Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →
What actually reaches you
The label counts the carrier, your body does not
Absorption
High 70 of 100 · absorbs well relative to other forms
Delivered daily
26.3 mg
Cost per 100 mg delivered
$3.81 comparative — uses the absorption score, not a measured percentage
Works better with
+
Thyme
Enhanced expectorant and bronchial support
Both provide expectorant and bronchial soothing effects · level C
+
Mullein
Synergistic respiratory soothing and expectorant support
Both provide respiratory tract soothing and mucus clearance · level C
+
Licorice Root
Enhanced anti-inflammatory and expectorant effects
Complementary anti-inflammatory and respiratory soothing properties · level CWhat not to take with Ivy Leaf
!
Respiratory Depressants
May interfere with respiratory depressant medications
Bronchodilator effects may oppose respiratory depression · mild significanceMedication interactions
Discuss these with a pharmacist before combiningMay enhance bronchodilator effects
What to do: Monitor respiratory function
May interfere with cough suppressant medications
What to do: Separate timing or choose one approach
Generally safe with most medications
What to do: Safe concurrent use
Available forms
Ivy Leaf Extract (Standardized Alpha-Hederin): Clinically proven, Natural bronchodilator, Cough relief, Good safety
Food sources
Standardized ivy leaf extracts
Concentrated alpha-hederin · 70
Ivy leaf tea (properly processed)
Lower concentration than extracts · 45
Not found in common foods
Specific medicinal preparation required · N/A
WARNING: Fresh ivy leaves are toxic
Do not use fresh plant · Dangerous
Too little
- Not applicable (herbal supplement, not essential nutrient):
- General symptoms addressed by ivy leaf:
- Persistent dry or productive cough
- Bronchial constriction and breathing difficulties
- Poor mucus clearance and respiratory congestion
- Chronic respiratory inflammation
- Reduced lung function and airway restriction
Too much
- Generally safe with minimal side effects:
- Allergic skin reactions in sensitive individuals
- Mild digestive upset
- Rare respiratory irritation
- Contact dermatitis with fresh plant
Who benefits most
acute-cough-bronchitis
Clinically proven cough relief for acute respiratory conditions
25-50mg daily (standardized extract)
chronic-cough-copd
Long-term bronchodilator support for chronic respiratory conditions
25-50mg daily long-term
asthma-bronchial-spasms
Natural bronchodilator for breathing difficulties and airway constriction
25-35mg daily
respiratory-mucus-congestion
Expectorant support for clearing respiratory secretions
25-50mg daily
seasonal-respiratory-support
Preventive respiratory support during allergy or cold season
25mg dailyWhere to buy it
Look for Ivy Leaf at 25-50mg per serving. The form that matters here is Ivy Leaf Extract (Standardized Alpha-Hederin).
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How it works
- Alpha-hederin saponins relax bronchial smooth muscle providing bronchodilator effects
- Expectorant saponins help thin and mobilize respiratory secretions
- Antispasmodic effects reduce cough reflex and bronchial spasms
- Anti-inflammatory compounds reduce respiratory tract inflammation
- Beta-2 agonist-like effects improve airway function
- Mucolytic properties help break down thick respiratory secretions
Key findings
what the evidence supports- Clinically proven effective for cough relief in multiple studies
- Significant bronchodilator effects demonstrated in research
- Good safety profile when properly processed and dosed
- Approved medicinal use in several European countries
Sources: NIH Examine.com · data reviewed 2026-08-02
Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →
Common questions
What are the benefits of Ivy Leaf?
Documented effects: Clinically proven cough relief; Bronchodilator and airway support; Expectorant and mucus clearance; Anti-inflammatory respiratory support. Scientifically validated reduction in cough frequency and severity
How much Ivy Leaf should you take per day?
The common daily range is 25-50mg. By goal — acute cough: 25-50mg daily; chronic respiratory: 25-50mg daily long-term; bronchial support: 25-35mg daily; expectorant support: 25-50mg daily.
When is the best time to take Ivy Leaf?
With meals. First effects are typically reported within 2-7 days for cough relief and expectorant effects.
What are the side effects of Ivy Leaf?
At excessive doses: Generally safe with minimal side effects:, Allergic skin reactions in sensitive individuals, Mild digestive upset, Rare respiratory irritation, Contact dermatitis with fresh plant. Safety rating at normal doses is 8 out of 10.
What should you not take with Ivy Leaf?
Separate it from Respiratory Depressants by two to four hours. May interfere with respiratory depressant medications
Does Ivy Leaf interact with medications?
Documented interactions with bronchodilator-medications, cough-suppressants, no-major-interactions. Discuss these with a pharmacist before combining.
How do you know if you need Ivy Leaf?
The marker is Generally not needed - assess through symptom improvement, optimal range Improved respiratory function and reduced cough. Common deficiency signs: Not applicable (herbal supplement, not essential nutrient):, General symptoms addressed by ivy leaf:, Persistent dry or productive cough, Bronchial constriction and breathing difficulties.