Appetite suppression and weight management
Helps reduce appetite and supports healthy weight management
Garcinia Cambogia
Tropical fruit extract rich in hydroxycitric acid traditionally used for appetite suppression and weight management support
Scientific nameGarcinia gummi-gutta
FormulaC6H8O8 (hydroxycitric acid)
Molecular weight208.12 g/mol
CAS27750-10-3
65
absorption score
6
safety / 10
25
USD per month
5
documented interactions
Check it against something
Garcinia Cambogia with:
- Amylase
- Ashwagandha
- Avocado Oil
- BCAA (Branched-Chain Amino Acids)
- Beetroot Powder
- Beta-Alanine
- Bifidobacterium lactis
- Bifidobacterium longum
- Bovine Collagen
- Caffeine
- Calcium
- Calcium Bone Formula
- Calcium Carbonate
- Casein Protein
- Chicken Collagen
- Choline (Bitartrate)
- Chondroitin Sulfate
- Chromium GTF
- Coconut Oil
- Collagen Peptides
- Comprehensive Immune Support Complex
- Comprehensive Multivitamin-Mineral Complex
- Creatine HCL
- Creatine Monohydrate
- D-Mannose
- DHA
- Electrolyte Blend
- EPA
- Fish Oil (EPA/DHA)
- Folate (5-MTHF)
- Ginger
- Iron Fumarate
- Iron Sulfate
- Joint Mobility Formula
- Keratin
- Krill Oil
- L-Carnitine
- L-Citrulline
- Lactase
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lipase
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Oxide
- Marine Collagen
- Melatonin
- Modafinil
- Olive Oil Extract
- Omega-3 + Curcumin + Vitamin D Triple Anti-Inflammatory Formula
- Papain
- Protease
- Saccharomyces boulardii
- Turmeric
- Vitamin B12 (Cyanocobalamin)
- Vitamin B12 (Methylcobalamin)
- Vitamin C (Ascorbic Acid)
- Vitamin C (Sodium Ascorbate)
- Vitamin D3
- Whey Protein
- Zinc Gluconate
Nothing found
75
out of 100
Works better together
Compatible. Timing differs, so follow each supplement's own window.
What it does
mechanism and evidence for each claimFat synthesis inhibition
Blocks conversion of carbohydrates to fat storage
Carbohydrate metabolism support
Supports healthy carbohydrate metabolism and glucose utilization
Cholesterol and lipid support
May help support healthy cholesterol and triglyceride levels
Energy and endurance enhancement
May improve energy levels and exercise endurance
Others take these for the same thing
Same goal, different mechanism — check any of them against this one
Ashwagandha
Stress management & energy
300-600mg
A
75%
Vitamin B12 (Cyanocobalamin)
Energy & nerve support
250-1000 mcg
A
70%
Coenzyme Q10 (CoQ10)
Heart health & cellular energy
100-200mg
A
10%
Phosphorus
Bone health & energy metabolism
700-1250mg
A
80%
Vitamin B3 (Niacinamide)
Energy & skin health (no flush)
100-1000 mg
A
88%
Berberine for Advanced Glucose Control and Metabolic Support
Blood sugar control & metabolic support
1500mg daily (500mg x3)
A
60%
Every pair we checked
12 combinations scored by the engine
Garcinia Cambogia + Caffeine
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Creatine Monohydrate
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Vitamin D3
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Calcium Carbonate
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Whey Protein
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Lactase
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Bovine Collagen
No documented interaction either way
No known interaction
70
Garcinia Cambogia + DHA
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Turmeric
No documented interaction either way
No known interaction
70
Garcinia Cambogia + Chromium GTF
Enhanced glucose metabolism and appetite control
Works better together
75
Garcinia Cambogia + Green Tea Extract (EGCG)
Synergistic weight management and metabolism support
Works better together
75
Garcinia Cambogia + Prebiotic Fiber Complex
Enhanced satiety and appetite control
Works better together
75
Dosage
Daily500-1500mg
Weight management500-1500mg daily
Appetite control500-1000mg before meals
Metabolic support500-1000mg daily
Cholesterol support500-1000mg daily
Before you take it
VeganYes
When to expect it
First Effects4-8 weeks for appetite suppression and initial weight benefits
Peak Benefits12-24 weeks for sustained weight management and metabolic support
Deficiency DevelopmentNot applicable - herbal supplement
Toxicity OnsetRare, mainly with very high doses or contaminated products
How to measure it
MarkerLiver enzymes (ALT, AST), lipid profile, fasting glucose
OptimalNormal liver function, improved lipid profile
Deficient belowNot applicable for herbal supplement
FrequencyEvery 3-6 months, especially monitoring liver function
What people actually reported to the FDA
CAERS, 92 reports naming it as the suspectMost reported effects
Named as the suspect
92 reports
of 100 that mention it at all
Serious outcome
74%
hospitalisation, emergency room or worse
Other Serious or Important Medical Event45
Hospitalization25
Other Outcome16
Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →
What actually reaches you
The label counts the carrier, your body does not
Absorption
High 65 of 100 · absorbs well relative to other forms
Delivered daily
650 mg
Cost per 100 mg delivered
$0.13 comparative — uses the absorption score, not a measured percentage
Works better with
+
Chromium
Enhanced glucose metabolism and appetite control
Both support healthy glucose metabolism and may reduce cravings · level C
+
Green Tea Extract
Synergistic weight management and metabolism support
Complementary mechanisms for fat burning and weight control · level C
+
Fiber Supplements
Enhanced satiety and appetite control
Both promote feelings of fullness and appetite regulation · level CWhat not to take with Garcinia Cambogia
!
High Refined Carb Meals
High carb intake may reduce effectiveness
Opposes carbohydrate metabolism control goals · moderate significance
!
Excessive Calories
Caloric excess may override appetite suppression benefits
Cannot overcome significantly excessive caloric intake · high significanceMedication interactions
Discuss these with a pharmacist before combiningMay affect blood sugar levels
What to do: Monitor blood glucose levels
May interact with serotonin-affecting medications
What to do: Monitor for serotonin effects
May enhance cholesterol-lowering effects
What to do: Monitor lipid levels
Available forms
Garcinia Cambogia Extract (Standardized 50-60% HCA): Appetite suppression, Fat synthesis blocking, Traditional use, Carb metabolism support
Food sources
Fresh garcinia cambogia fruit
Natural HCA content in rind · 60
Dried garcinia rind powder
Concentrated HCA content · 65
Standardized extracts
Concentrated HCA (50-60%) · 65
Traditional curry preparations
Moderate HCA content · 50
Too little
- Not applicable (herbal supplement, not essential nutrient):
- General symptoms addressed by garcinia cambogia:
- Excessive appetite and food cravings
- Difficulty managing weight and fat storage
- Poor carbohydrate metabolism and sugar cravings
- High cholesterol and triglyceride levels
- Low energy and poor exercise endurance
Too much
- Generally safe with some considerations:
- Rare liver enzyme elevation with high doses
- Digestive upset and nausea
- Headaches (uncommon)
- Important to use high-quality, pure products
Who benefits most
weight-management-appetite-control
Natural appetite suppression and weight management support
500-1500mg daily (standardized to 50-60% HCA)
carb-cravings-sugar-addiction
Appetite control specifically for carbohydrate and sugar cravings
500-1000mg daily before meals
metabolic-syndrome-support
Metabolic support for those with metabolic syndrome risk factors
500-1000mg daily
cholesterol-lipid-support
Support for healthy cholesterol and triglyceride levels
500-1000mg daily
exercise-performance-endurance
Energy and endurance support for physical activity
500mg dailyWhere to buy it
Look for Garcinia Cambogia at 500-1500mg per serving. The form that matters here is Garcinia Cambogia Extract (Standardized 50-60% HCA).
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What else affects it
Beyond other supplements
!
High refined carb meals
High carb intake may reduce effectiveness
Opposes carbohydrate metabolism control goals
!
Excessive calories
Caloric excess may override appetite suppression benefits
Cannot overcome significantly excessive caloric intakeHow it works
- HCA inhibits ATP citrate lyase enzyme blocking conversion of carbohydrates to fat
- Increases serotonin levels in brain reducing appetite and food cravings
- Redirects carbohydrate metabolism toward glycogen storage rather than fat synthesis
- May improve leptin sensitivity enhancing satiety signals
- Supports healthy glucose metabolism and insulin sensitivity
- Potential cholesterol-lowering effects through reduced fat synthesis
Key findings
what the evidence supports- Mixed clinical evidence for weight loss with modest effects
- Some support for appetite suppression and fat synthesis inhibition
- Important quality and safety considerations with supplements
- More research needed to establish consistent effectiveness
Sources: NIH Examine.com · data reviewed 2026-08-02
Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →
Common questions
What are the benefits of Garcinia Cambogia?
Documented effects: Appetite suppression and weight management; Fat synthesis inhibition; Carbohydrate metabolism support; Cholesterol and lipid support. Helps reduce appetite and supports healthy weight management
How much Garcinia Cambogia should you take per day?
The common daily range is 500-1500mg. By goal — weight management: 500-1500mg daily; appetite control: 500-1000mg before meals; metabolic support: 500-1000mg daily; cholesterol support: 500-1000mg daily.
When is the best time to take Garcinia Cambogia?
Before meals. First effects are typically reported within 4-8 weeks for appetite suppression and initial weight benefits.
What are the side effects of Garcinia Cambogia?
At excessive doses: Generally safe with some considerations:, Rare liver enzyme elevation with high doses, Digestive upset and nausea, Headaches (uncommon), Important to use high-quality, pure products. Safety rating at normal doses is 6 out of 10.
What should you not take with Garcinia Cambogia?
Separate it from High Refined Carb Meals, Excessive Calories by two to four hours. High carb intake may reduce effectiveness
Does Garcinia Cambogia interact with medications?
Documented interactions with diabetes-medications, antidepressants-ssri, cholesterol-medications. Discuss these with a pharmacist before combining.
How do you know if you need Garcinia Cambogia?
The marker is Liver enzymes (ALT, AST), lipid profile, fasting glucose, optimal range Normal liver function, improved lipid profile. Common deficiency signs: Not applicable (herbal supplement, not essential nutrient):, General symptoms addressed by garcinia cambogia:, Excessive appetite and food cravings, Difficulty managing weight and fat storage.