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Avocado Oil

Premium avocado-derived oil rich in omega-9 fatty acids, antioxidants, and fat-soluble vitamins supporting cardiovascular health and nutrient absorption

Scientific namePersea americana oil FormulaRich in oleic acid, palmitic acid, and linoleic acid Molecular weightVariable triglyceride mixture g/mol CAS8024-32-6
95 absorption score
9 safety / 10
35 USD per month
5 documented interactions

Check it against something

No documented links

Avocado Oil with:

Compatibility score 70 out of 100
70 out of 100
No known interaction No documented interaction. Standard timing for each applies.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Cardiovascular health and cholesterol support

Supports heart health and improves cholesterol profiles

High oleic acid content reduces LDL and increases HDL cholesterol Evidence B-grade 6-12 weeks

Enhanced nutrient absorption

Dramatically improves absorption of fat-soluble vitamins and carotenoids

Healthy fats facilitate absorption of vitamins A, D, E, K and antioxidants Evidence A-grade Immediate to 4 weeks

Anti-inflammatory and antioxidant protection

Provides potent anti-inflammatory and antioxidant effects

Vitamin E, carotenoids, and omega-9s reduce inflammation and oxidative stress Evidence B-grade 2-8 weeks

Skin health and wound healing

Supports skin health, healing, and anti-aging when used internally and topically

Essential fatty acids and antioxidants support skin structure and repair Evidence B-grade 4-12 weeks

High-heat cooking stability

Excellent stability for high-temperature cooking without oxidation

High smoke point and monounsaturated fat content resist oxidation Evidence A-grade Immediate

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Every pair we checked

12 combinations scored by the engine
Avocado Oil + Caffeine No documented interaction either way No known interaction 70
Avocado Oil + Creatine Monohydrate No documented interaction either way No known interaction 70
Avocado Oil + Vitamin D3 No documented interaction either way No known interaction 70
Avocado Oil + Calcium Carbonate No documented interaction either way No known interaction 70
Avocado Oil + Whey Protein No documented interaction either way No known interaction 70
Avocado Oil + Lactase No documented interaction either way No known interaction 70
Avocado Oil + Bovine Collagen No documented interaction either way No known interaction 70
Avocado Oil + DHA No documented interaction either way No known interaction 70
Avocado Oil + Turmeric No documented interaction either way No known interaction 70
Avocado Oil + Fish Oil (EPA/DHA) No documented interaction either way No known interaction 70
Avocado Oil + Magnesium Oxide No documented interaction either way No known interaction 70
Avocado Oil + Marine Collagen No documented interaction either way No known interaction 70

Dosage

With meals
Daily15-30ml
Cardiovascular support15-30ml daily
Nutrient absorption15ml with meals
Cooking useAs needed for food preparation
Skin health15-30ml daily

When to expect it

First EffectsImmediate for nutrient absorption, 2-4 weeks for other benefits
Peak Benefits8-16 weeks for sustained cardiovascular and health benefits
Deficiency DevelopmentNot applicable - avocado oil is not essential
Toxicity OnsetVery rare, mainly caloric excess or allergic reactions

How to measure it

$150-200
MarkerLipid panel, carotenoid levels, fat-soluble vitamin status
OptimalImproved cholesterol ratios, elevated carotenoids, adequate fat-soluble vitamins
Deficient belowPoor lipid profile, low carotenoid status
FrequencyEvery 6-12 months for nutritional status assessment

What people actually reported to the FDA

CAERS, 1 reports naming it as the suspect

Most reported effects

Blood potassium increased 1
Named as the suspect 1 reports of 9 that mention it at all
Serious outcome 100% hospitalisation, emergency room or worse
Hospitalization1
Visited Emergency Room1

Reports are voluntary and unverified — they record what someone experienced while taking something, not what the compound caused. Counts skew towards products people take a lot of, and a serious outcome is more likely to be reported than a mild one, so these are not rates. How we filter them →

What actually reaches you

The label counts the carrier, your body does not
Absorption Very high 95 of 100 · best absorbed form of this compound
Delivered daily 21.4 mg
Cost per 100 mg delivered $5.46 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented
+
Carotenoid Rich Vegetables

Dramatically enhanced carotenoid absorption and bioavailability

Healthy fats increase carotenoid absorption by 3-5 times · level A
+
Fat Soluble Vitamins

Enhanced absorption of vitamins A, D, E, K

Dietary fats essential for fat-soluble vitamin absorption · level A
+
Antioxidant Spices

Enhanced absorption of curcumin and other fat-soluble antioxidants

Healthy fats improve bioavailability of lipophilic compounds · level B

What not to take with Avocado Oil

2 documented
!
Excessive Heat Storage

High heat and light exposure reduce oil quality

Oxidation destroys beneficial compounds and creates harmful products · moderate significance
!
Trans Fats

Trans fats counteract avocado oil's cardiovascular benefits

Trans fats promote inflammation and cardiovascular disease · high significance

Medication interactions

Discuss these with a pharmacist before combining
anticoagulants Minor

Vitamin K content may affect blood clotting

What to do: Consistent intake if on warfarin

cholesterol-medications None

May enhance cholesterol-lowering effects

What to do: Beneficial combination

Available forms

bioavailability compared
Cold-Pressed Avocado Oil (Extra Virgin) 95

Cold-Pressed Avocado Oil (Extra Virgin): High smoke point, Nutrient absorption, Heart healthy, Cooking versatility

Food sources

before you supplement
Cold-pressed avocado oil Pure oil (15-30ml daily) · 95
Fresh avocados Natural oil content in fruit · 90
Avocado oil supplements Concentrated capsules · 85
Avocado-based products Various food preparations · 80

Too little

deficiency signs
  • No specific avocado oil deficiency as it's not essential:
  • Poor absorption of fat-soluble vitamins from vegetables
  • Suboptimal carotenoid status despite adequate intake
  • Missing cardiovascular benefits of healthy monounsaturated fats
  • Reduced skin health and healing capacity
  • Increased oxidative stress without adequate healthy fats

Too much

toxicity signs
  • Extremely safe with minimal side effects:
  • Weight gain with excessive caloric intake
  • Allergic reactions in avocado-sensitive individuals
  • Digestive upset with very large amounts
  • Generally well tolerated by most people

Who benefits most

cardiovascular-health-support

Heart health optimization and cholesterol management

1-2 tablespoons daily (15-30ml)
nutrient-absorption-enhancement

Improved absorption of fat-soluble vitamins and antioxidants

1 tablespoon with meals (15ml)
high-heat-cooking-needs

Stable cooking oil for high-temperature food preparation

As needed for cooking
skin-health-support

Internal and topical skin health and anti-aging support

1-2 tablespoons daily
anti-inflammatory-support

Natural anti-inflammatory and antioxidant protection

1-2 tablespoons daily

Where to buy it

compare forms first

Look for Avocado Oil at 15-30ml per serving. The form that matters here is Cold-Pressed Avocado Oil (Extra Virgin).

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What else affects it

Beyond other supplements
!
Excessive heat storage

High heat and light exposure reduce oil quality

Oxidation destroys beneficial compounds and creates harmful products
!
Trans fats

Trans fats counteract avocado oil's cardiovascular benefits

Trans fats promote inflammation and cardiovascular disease

How it works

  • High oleic acid content improves cholesterol ratios and cardiovascular health
  • Facilitates absorption of fat-soluble vitamins A, D, E, K from foods
  • Vitamin E and carotenoids provide antioxidant protection against cellular damage
  • Monounsaturated fats support healthy inflammatory responses
  • Essential fatty acids support skin barrier function and wound healing
  • High smoke point prevents formation of harmful oxidation products during cooking

Key findings

what the evidence supports
  • Strong evidence for enhanced nutrient absorption
  • Good research on cardiovascular health benefits
  • Proven stability for high-heat cooking applications
  • Excellent safety profile with minimal side effects

Sources: NIH Examine.com · data reviewed 2026-08-02

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Avocado Oil?

Documented effects: Cardiovascular health and cholesterol support; Enhanced nutrient absorption; Anti-inflammatory and antioxidant protection; Skin health and wound healing. Supports heart health and improves cholesterol profiles

How much Avocado Oil should you take per day?

The common daily range is 15-30ml. By goal — cardiovascular support: 15-30ml daily; nutrient absorption: 15ml with meals; cooking use: As needed for food preparation; skin health: 15-30ml daily.

When is the best time to take Avocado Oil?

With meals. First effects are typically reported within Immediate for nutrient absorption, 2-4 weeks for other benefits.

What are the side effects of Avocado Oil?

At excessive doses: Extremely safe with minimal side effects:, Weight gain with excessive caloric intake, Allergic reactions in avocado-sensitive individuals, Digestive upset with very large amounts, Generally well tolerated by most people. Safety rating at normal doses is 9 out of 10.

What should you not take with Avocado Oil?

Separate it from Excessive Heat Storage, Trans Fats by two to four hours. High heat and light exposure reduce oil quality

Does Avocado Oil interact with medications?

Documented interactions with anticoagulants, cholesterol-medications. Discuss these with a pharmacist before combining.

How do you know if you need Avocado Oil?

The marker is Lipid panel, carotenoid levels, fat-soluble vitamin status, optimal range Improved cholesterol ratios, elevated carotenoids, adequate fat-soluble vitamins. Common deficiency signs: No specific avocado oil deficiency as it's not essential:, Poor absorption of fat-soluble vitamins from vegetables, Suboptimal carotenoid status despite adequate intake, Missing cardiovascular benefits of healthy monounsaturated fats.

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