Magnesium L-Threonate + Melatonin
Compatible. Timing differs, so follow each supplement's own window.
Verdict
Timing plan
Can be taken togetherNothing blocks them — the same window is what produces the synergy below.
What helps
Melatonin → Magnesium L-Threonate
Complementary effects on nervous system relaxation · level BSide by side
| Magnesium L-Threonate | Melatonin | |
|---|---|---|
| Bioavailability | 95% | 50% |
| Elemental mineral | 8.3% | —% |
| Cost per 100 mg absorbed | $1.69 | $38.1 |
| Safety rating | 8/10 | 8/10 |
| Cost per month | $120 | $10 |
| Daily dose | 2000-4000 mg | 0.5-3mg |
| Best timing | Morning afternoon divided | 30 60 minutes before bed |
| Evidence level | B | A |
How this score was built
- Baseline for any untested pair: 70
- +8 — synergy at evidence level B
- = 78 out of 100
Where to buy
Buying both? Check the timing plan above so they do not cancel each other out.
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Common questions
Can you take Magnesium L-Threonate and Melatonin together?
Compatible. Timing differs, so follow each supplement's own window. The pair scores 78 out of 100, based on 1 documented interaction records.
What should you not take with Magnesium L-Threonate?
Nothing in this pairing clashes. Its own page lists everything Magnesium L-Threonate is documented to conflict with.
When should you take Magnesium L-Threonate and Melatonin?
Magnesium L-Threonate: Morning afternoon divided. Melatonin: 30 60 minutes before bed. The same window works for both.