Gotu Kola

Traditional brain and circulation herb that enhances cognitive function, wound healing, and vascular health while promoting longevity

Scientific nameCentella asiatica FormulaComplex triterpenoids and asiaticoside Molecular weightVariable bioactive compounds g/mol CASVarious natural compounds

70 absorption score

7 safety / 10

30 USD per month

5 documented interactions

Check it against something

Evidence level C

Gotu Kola with:

75 out of 100

Works better together Take together — same timing window amplifies the synergy.

Check it against your whole stack →

What it does

mechanism and evidence for each claim

Enhanced cognitive function and memory

Improves memory, concentration, and mental clarity

Triterpenoids support neural growth and neurotransmitter function Evidence C-grade 4-8 weeks

Improved circulation and vascular health

Enhances blood flow and strengthens blood vessel walls

Asiaticoside improves venous tone and capillary integrity Evidence B-grade 6-12 weeks

Wound healing and skin health

Accelerates wound healing and improves skin appearance

Stimulates collagen production and cellular regeneration Evidence B-grade 2-8 weeks

Anxiety and stress reduction

Reduces anxiety and promotes calm mental state

Modulates neurotransmitters and stress response pathways Evidence C-grade 2-6 weeks

Longevity and anti-aging support

Traditional longevity herb supporting healthy aging

Antioxidant effects and cellular protection mechanisms Evidence C-grade Long-term use

Others take these for the same thing

Same goal, different mechanism — check any of them against this one

Vitamin B12 (Cyanocobalamin) Energy & nerve support 250-1000 mcg A 70% Coenzyme Q10 (CoQ10) Heart health & cellular energy 100-200mg A 10% Fish Oil (EPA/DHA) Heart & brain health 1-2g EPA/DHA A 85% L-Theanine Calm focus & stress relief 100-400mg B 90% Psyllium Husk Digestive health & cholesterol support 5-15g A 95% Vitamin B8 (Inositol) Mental health & PCOS support 2-18g (condition dependent) B 95%

Every pair we checked

12 combinations scored by the engine

Gotu Kola + Caffeine No documented interaction either way No known interaction 70

Gotu Kola + Creatine Monohydrate No documented interaction either way No known interaction 70

Gotu Kola + Calcium Carbonate No documented interaction either way No known interaction 70

Gotu Kola + Whey Protein No documented interaction either way No known interaction 70

Gotu Kola + Lactase No documented interaction either way No known interaction 70

Gotu Kola + Bovine Collagen No documented interaction either way No known interaction 70

Gotu Kola + DHA No documented interaction either way No known interaction 70

Gotu Kola + Turmeric No documented interaction either way No known interaction 70

Gotu Kola + Fish Oil (EPA/DHA) No documented interaction either way No known interaction 70

Gotu Kola + Ginkgo Biloba Enhanced circulation and cognitive benefits Works better together 75

Gotu Kola + Bacopa Monnieri Enhanced cognitive and memory benefits Works better together 75

Gotu Kola + Vitamin D3 Enhanced collagen synthesis and wound healing Works better together 78

Dosage

With meals

Daily300-1500mg

Cognitive enhancement500-1000mg daily

Circulation support500-1500mg daily

Wound healing500-1000mg daily

Anxiety reduction300-600mg daily

Before you take it

VeganYes

When to expect it

First Effects2-4 weeks for circulation and initial cognitive benefits

Peak Benefits8-12 weeks for sustained cognitive and vascular benefits

Deficiency DevelopmentReturn to baseline cognitive and circulation function

Toxicity OnsetRare with normal doses, risk with high doses

How to measure it

$100-200

MarkerLiver function tests, circulation markers, or cognitive assessments

OptimalNormal liver function, improved circulation markers

Deficient belowNot applicable for supplement

FrequencyMonitor liver function if using high doses long-term

What actually reaches you

The label counts the carrier, your body does not

Absorption High 70 of 100 · absorbs well relative to other forms

Delivered daily 630 mg

Cost per 100 mg delivered $0.16 comparative — uses the absorption score, not a measured percentage

Works better with

3 documented

Ginkgo Biloba

Enhanced circulation and cognitive benefits

Complementary circulation-enhancing compounds · level C

Vitamin C

Enhanced collagen synthesis and wound healing

Both support collagen production and healing · level B

Bacopa Monnieri

Enhanced cognitive and memory benefits

Complementary nootropic herbs for brain health · level C

What not to take with Gotu Kola

2 documented

Sedatives Alcohol

May enhance sedative effects

Gotu kola may have mild sedating properties · minor significance

Hepatotoxic Substances

May increase liver toxicity risk

Additive stress on liver function · moderate significance

Medication interactions

Discuss these with a pharmacist before combining

sedatives-sleep-medications Minor

May enhance sedative effects

What to do: Monitor for increased drowsiness

hepatotoxic-medications Moderate

May increase liver toxicity risk

What to do: Monitor liver function

diabetes-medications Minor

May affect blood sugar levels

What to do: Monitor blood glucose

Available forms

bioavailability compared

Standardized Asiaticoside Extract 80

Whole Herb Extract 70

Fresh Herb/Juice 60

Dried Herb Powder 55

Standardized Asiaticoside Extract: Standardized potency, Research component, Higher concentration, Quality controlled

Whole Herb Extract: Complete spectrum, Traditional use, Multiple compounds, More affordable

Fresh Herb/Juice: Whole plant, Traditional preparation, Very affordable, Natural form

Dried Herb Powder: Traditional form, Complete spectrum, Lower cost, Widely available

Food sources

before you supplement

Fresh gotu kola leaves Edible vegetable, lower medicinal potency · 50

Gotu kola extract supplements 300-1500mg per capsule · 70-80

Gotu kola tea Lower concentration · 45

Gotu kola juice Traditional preparation · 60

Too little

deficiency signs

Not essential - but symptoms addressed by gotu kola:
Poor circulation and varicose veins
Cognitive decline and memory problems
Slow wound healing and poor skin health
Anxiety and mental agitation
Poor vascular integrity
Accelerated aging and cellular damage

Too much

toxicity signs

Generally safe but potential concerns:
Liver toxicity with high doses or long-term use
Skin sensitivity and contact dermatitis
Drowsiness and fatigue
Rare allergic reactions

Who benefits most

cognitive-enhancement-memory

Traditional brain food for memory and mental clarity

500-1000mg daily

circulation-vascular-health

Excellent for improving circulation and vein health

500-1500mg daily

wound-healing-skin-health

Accelerates healing and improves skin appearance

500-1000mg daily or topical use

anxiety-stress-management

May help reduce anxiety and promote calm

300-600mg daily

longevity-anti-aging

Traditional longevity herb for healthy aging

300-600mg daily

Where to buy it

compare forms first

Look for Gotu Kola at 300-1500mg per serving. The form that matters here is Standardized Asiaticoside Extract.

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How it works

Asiaticoside and madecassoside improve venous tone and circulation
Triterpenoids support neural growth factor and brain function
Stimulates collagen synthesis and wound healing processes
Antioxidant compounds protect against cellular damage
Modulates GABA and other neurotransmitters for calming effects
Enhances microcirculation and capillary integrity

Key findings

what the evidence supports

Good evidence for circulation improvement and wound healing
Limited evidence for cognitive enhancement
Generally safe but monitor for liver toxicity with high doses
Most research focused on topical and circulation applications

Sources: NIH Examine.com · data reviewed 2026-08-01

Compiled by Denis, who maintains this database and holds no medical qualification — every figure here is sourced or derived, never asserted. How we calculate it →

Common questions

What are the benefits of Gotu Kola?

Documented effects: Enhanced cognitive function and memory; Improved circulation and vascular health; Wound healing and skin health; Anxiety and stress reduction. Improves memory, concentration, and mental clarity

How much Gotu Kola should you take per day?

The common daily range is 300-1500mg. By goal — cognitive enhancement: 500-1000mg daily; circulation support: 500-1500mg daily; wound healing: 500-1000mg daily; anxiety reduction: 300-600mg daily.

When is the best time to take Gotu Kola?

With meals. First effects are typically reported within 2-4 weeks for circulation and initial cognitive benefits.

What are the side effects of Gotu Kola?

At excessive doses: Generally safe but potential concerns:, Liver toxicity with high doses or long-term use, Skin sensitivity and contact dermatitis, Drowsiness and fatigue, Rare allergic reactions. Safety rating at normal doses is 7 out of 10.

What should you not take with Gotu Kola?

Separate it from Sedatives Alcohol, Hepatotoxic Substances by two to four hours. May enhance sedative effects

Does Gotu Kola interact with medications?

Documented interactions with sedatives-sleep-medications, hepatotoxic-medications, diabetes-medications. Discuss these with a pharmacist before combining.

How do you know if you need Gotu Kola?

The marker is Liver function tests, circulation markers, or cognitive assessments, optimal range Normal liver function, improved circulation markers. Common deficiency signs: Not essential - but symptoms addressed by gotu kola:, Poor circulation and varicose veins, Cognitive decline and memory problems, Slow wound healing and poor skin health.

Taken for

52 Brain & Focus

Caffeine · DHA · Fish Oil (EPA/DHA)

52 Heart

Fish Oil (EPA/DHA) · EPA · Olive Oil Extract