Check a pair

Vitamin B12 and Folate together

Checked on Vitamin B12 (Cyanocobalamin) and Vitamin B9 (Folic Acid) — the best-absorbed forms people actually buy. Other forms of the same two behave the same way here: the interaction belongs to the mineral, not to the carrier.

Take together — same timing window amplifies the synergy.

99 compatibility
4 synergies
0 conflicts

Verdict

Evidence level A
Compatibility score 99 out of 100
99 out of 100
Works better together Take together — same timing window amplifies the synergy.

Timing plan

Can be taken together
Vitamin B12 (Cyanocobalamin) Morning with food 250-1000 mcg
Vitamin B9 (Folic Acid) Morning with food 400-800 mcg

Nothing blocks them — the same window is what produces the synergy below.

What helps

4 documented
+
Both involved in homocysteine metabolism

Vitamin B12 (Cyanocobalamin) → Vitamin B9 (Folic Acid)

Sequential steps in methylation pathway · level A
+
Work together in methylation and DNA synthesis

Vitamin B9 (Folic Acid) → Vitamin B12 (Cyanocobalamin)

Complementary roles in one-carbon metabolism · level A
+
Both involved in homocysteine metabolism

Vitamin B9 (Folic Acid) → Vitamin B12 (Cyanocobalamin)

Sequential steps in methylation pathway · level A
+
Protects folate from oxidation

Vitamin B9 (Folic Acid) → Vitamin B12 (Cyanocobalamin)

Antioxidant protection and folate regeneration · level B

Side by side

Vitamin B12 (Cyanocobalamin)Vitamin B9 (Folic Acid)
Absorption score 70/100 85/100
Cost per 10 mg delivered $6.1 $3.27
Safety rating 9/10 8/10
Cost per month $8 $5
Daily dose 250-1000 mcg 400-800 mcg
Best timing Morning with food Morning with food
Evidence level A A

How this score was built

  • Baseline for any untested pair: 70
  • +12 — synergy at evidence level A
  • +12 — synergy at evidence level A
  • +12 — synergy at evidence level A
  • +8 — synergy at evidence level B
  • = 99 out of 100

Where to buy

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Buying both? Check the timing plan above so they do not cancel each other out.

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Common questions

Can you take Vitamin B12 (Cyanocobalamin) and Vitamin B9 (Folic Acid) together?

Take together — same timing window amplifies the synergy. The pair scores 99 out of 100, based on 4 documented interaction records.

What should you not take with Vitamin B12 (Cyanocobalamin)?

Nothing in this pairing clashes. Its own page lists everything Vitamin B12 (Cyanocobalamin) is documented to conflict with.

When should you take Vitamin B12 (Cyanocobalamin) and Vitamin B9 (Folic Acid)?

Vitamin B12 (Cyanocobalamin): Morning with food. Vitamin B9 (Folic Acid): Morning with food. The same window works for both.

Where to go next