Heme Iron + Folate (5-MTHF)
Compatible. Timing differs, so follow each supplement's own window.
0
compatibility
0
synergies
0
conflicts
Verdict
82
out of 100
Works better together
Compatible. Timing differs, so follow each supplement's own window.
Timing plan
Can be taken together
Heme Iron
Anytime with or without food
18-30 mg
Folate (5-MTHF)
Morning with food
400-800 mcg
Nothing blocks them — the same window is what produces the synergy below.
What helps
+
Essential cofactor for red blood cell production
Heme Iron → Folate (5-MTHF)
Required for DNA synthesis during red blood cell formation · level ASide by side
| Heme Iron | Folate (5-MTHF) | |
|---|---|---|
| Bioavailability | 85% | 95% |
| Safety rating | 10/10 | 9/10 |
| Cost per month | $120 | $20 |
| Daily dose | 18-30 mg | 400-800 mcg |
| Best timing | Anytime with or without food | Morning with food |
| Evidence level | A | A |
How this score was built
- Baseline for any untested pair: 70
- +12 — synergy at evidence level A
- = 82 out of 100
Where to buy
Buying both? Check the timing plan above so they do not cancel each other out.
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Common questions
Can you take Heme Iron and Folate (5-MTHF) together?
Compatible. Timing differs, so follow each supplement's own window. The pair scores 82 out of 100, based on 1 documented interaction records.
What should you not take with Heme Iron?
Nothing in this pairing clashes. Its own page lists everything Heme Iron is documented to conflict with.
When should you take Heme Iron and Folate (5-MTHF)?
Heme Iron: Anytime with or without food. Folate (5-MTHF): Morning with food. The same window works for both.